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Schlafen4(+)-MDSC in Helicobacter-induced gastric metaplasia reveals role for GTPases

INTRODUCTION: MDSCs express SCHLAFEN 4 (SLFN4) in Helicobacter-infected stomachs coincident with spasmolytic polypeptide-expressing metaplasia (SPEM), a precursor of gastric cancer. We aimed to characterize SLFN4(+) cell identity and the role of Slfn4 in these cells. METHODS: Single-cell RNA sequenc...

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Detalles Bibliográficos
Autores principales:	Ding, Lin, Sheriff, Sulaiman, Sontz, Ricky A., Merchant, Juanita L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272601/ https://www.ncbi.nlm.nih.gov/pubmed/37334372 http://dx.doi.org/10.3389/fimmu.2023.1139391

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