Cargando…

Trends in metabolic indicators and microvascular complications in Chinese adults with newly diagnosed type 2 diabetes: A retrospective, single-centre study of twenty-years

BACKGROUND: The purpose of this study is to assess metabolic indicators and trends in microvascular complications among Chinese adults with newly diagnosed type 2 diabetes during 2000–2020. METHODS: 3,907 patients were included and divided into three groups according to a time period of 7 years. Thi...

Descripción completa

Detalles Bibliográficos
Autores principales: Shi, Lintao, Xue, Jing, Zhao, Weibo, Cheng, Yuxia, Wang, Jianjun, Xu, Zhangrong, Wang, Aihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272657/
https://www.ncbi.nlm.nih.gov/pubmed/37300432
http://dx.doi.org/10.1177/14791641231179867
_version_ 1785059546832568320
author Shi, Lintao
Xue, Jing
Zhao, Weibo
Cheng, Yuxia
Wang, Jianjun
Xu, Zhangrong
Wang, Aihong
author_facet Shi, Lintao
Xue, Jing
Zhao, Weibo
Cheng, Yuxia
Wang, Jianjun
Xu, Zhangrong
Wang, Aihong
author_sort Shi, Lintao
collection PubMed
description BACKGROUND: The purpose of this study is to assess metabolic indicators and trends in microvascular complications among Chinese adults with newly diagnosed type 2 diabetes during 2000–2020. METHODS: 3,907 patients were included and divided into three groups according to a time period of 7 years. This study analyzed trends in proportions of patients reached therapeutic targets of blood glucose, pressure and lipids, and trends in albuminuria, retinopathy, and peripheral neuropathy. RESULTS: In the past 20 years, the age of adults with newly diagnosed type 2 diabetes tended to be younger, and the proportion of female patients increased. There seemed no improvements in blood glucose and pressure. The rate of awareness and treatment on target of hypertension was less than 50%. There was a significant decrease in the prevalence of retinopathy, but no changes in nephropathy or peripheral neuropathy. Complications were more common for patients who were smoker, male, or with hypertension and obesity. CONCLUSIONS: Over the past two decades, there have been encouraging reductions in retinopathy in Chinese adults with newly diagnosed diabetes, but no significant change in albuminuria and peripheral neuropathy. It may be related to the low awareness of diabetes and insufficient controlled blood glucose, pressure and lipids on target.
format Online
Article
Text
id pubmed-10272657
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher SAGE Publications
record_format MEDLINE/PubMed
spelling pubmed-102726572023-06-17 Trends in metabolic indicators and microvascular complications in Chinese adults with newly diagnosed type 2 diabetes: A retrospective, single-centre study of twenty-years Shi, Lintao Xue, Jing Zhao, Weibo Cheng, Yuxia Wang, Jianjun Xu, Zhangrong Wang, Aihong Diab Vasc Dis Res Original Article BACKGROUND: The purpose of this study is to assess metabolic indicators and trends in microvascular complications among Chinese adults with newly diagnosed type 2 diabetes during 2000–2020. METHODS: 3,907 patients were included and divided into three groups according to a time period of 7 years. This study analyzed trends in proportions of patients reached therapeutic targets of blood glucose, pressure and lipids, and trends in albuminuria, retinopathy, and peripheral neuropathy. RESULTS: In the past 20 years, the age of adults with newly diagnosed type 2 diabetes tended to be younger, and the proportion of female patients increased. There seemed no improvements in blood glucose and pressure. The rate of awareness and treatment on target of hypertension was less than 50%. There was a significant decrease in the prevalence of retinopathy, but no changes in nephropathy or peripheral neuropathy. Complications were more common for patients who were smoker, male, or with hypertension and obesity. CONCLUSIONS: Over the past two decades, there have been encouraging reductions in retinopathy in Chinese adults with newly diagnosed diabetes, but no significant change in albuminuria and peripheral neuropathy. It may be related to the low awareness of diabetes and insufficient controlled blood glucose, pressure and lipids on target. SAGE Publications 2023-06-10 /pmc/articles/PMC10272657/ /pubmed/37300432 http://dx.doi.org/10.1177/14791641231179867 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Article
Shi, Lintao
Xue, Jing
Zhao, Weibo
Cheng, Yuxia
Wang, Jianjun
Xu, Zhangrong
Wang, Aihong
Trends in metabolic indicators and microvascular complications in Chinese adults with newly diagnosed type 2 diabetes: A retrospective, single-centre study of twenty-years
title Trends in metabolic indicators and microvascular complications in Chinese adults with newly diagnosed type 2 diabetes: A retrospective, single-centre study of twenty-years
title_full Trends in metabolic indicators and microvascular complications in Chinese adults with newly diagnosed type 2 diabetes: A retrospective, single-centre study of twenty-years
title_fullStr Trends in metabolic indicators and microvascular complications in Chinese adults with newly diagnosed type 2 diabetes: A retrospective, single-centre study of twenty-years
title_full_unstemmed Trends in metabolic indicators and microvascular complications in Chinese adults with newly diagnosed type 2 diabetes: A retrospective, single-centre study of twenty-years
title_short Trends in metabolic indicators and microvascular complications in Chinese adults with newly diagnosed type 2 diabetes: A retrospective, single-centre study of twenty-years
title_sort trends in metabolic indicators and microvascular complications in chinese adults with newly diagnosed type 2 diabetes: a retrospective, single-centre study of twenty-years
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272657/
https://www.ncbi.nlm.nih.gov/pubmed/37300432
http://dx.doi.org/10.1177/14791641231179867
work_keys_str_mv AT shilintao trendsinmetabolicindicatorsandmicrovascularcomplicationsinchineseadultswithnewlydiagnosedtype2diabetesaretrospectivesinglecentrestudyoftwentyyears
AT xuejing trendsinmetabolicindicatorsandmicrovascularcomplicationsinchineseadultswithnewlydiagnosedtype2diabetesaretrospectivesinglecentrestudyoftwentyyears
AT zhaoweibo trendsinmetabolicindicatorsandmicrovascularcomplicationsinchineseadultswithnewlydiagnosedtype2diabetesaretrospectivesinglecentrestudyoftwentyyears
AT chengyuxia trendsinmetabolicindicatorsandmicrovascularcomplicationsinchineseadultswithnewlydiagnosedtype2diabetesaretrospectivesinglecentrestudyoftwentyyears
AT wangjianjun trendsinmetabolicindicatorsandmicrovascularcomplicationsinchineseadultswithnewlydiagnosedtype2diabetesaretrospectivesinglecentrestudyoftwentyyears
AT xuzhangrong trendsinmetabolicindicatorsandmicrovascularcomplicationsinchineseadultswithnewlydiagnosedtype2diabetesaretrospectivesinglecentrestudyoftwentyyears
AT wangaihong trendsinmetabolicindicatorsandmicrovascularcomplicationsinchineseadultswithnewlydiagnosedtype2diabetesaretrospectivesinglecentrestudyoftwentyyears