Cargando…

Impact of sex and APOE-ε4 genotype on patterns of regional brain atrophy in Alzheimer's disease and healthy aging

Alzheimer's Disease (AD) is a heterogeneous disease that disproportionately affects women and people with the APOE-ε4 susceptibility gene. We aim to describe the not-well-understood influence of both risk factors on the dynamics of brain atrophy in AD and healthy aging. Regional cortical thinni...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sauty, Benoît, Durrleman, Stanley
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Neurology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272760/ https://www.ncbi.nlm.nih.gov/pubmed/37333001 http://dx.doi.org/10.3389/fneur.2023.1161527

Ejemplares similares

APOEε4 Genotype Is Related to Brain Amyloid Among Mexican Americans in the HABS-HD Study
por: O'Bryant, Sid E., et al.
Publicado: (2022)

Association of sex and APOE ε4 with brain tau deposition and atrophy in older adults with Alzheimer's disease
por: Yan, Shaozhen, et al.
Publicado: (2020)

The Relationship of APOE ε4, Race, and Sex on the Age of Onset and Risk of Dementia
por: Powell, Danielle S., et al.
Publicado: (2021)

Sex and APOE ε4 genotype modify the Alzheimer’s disease serum metabolome
por: Arnold, Matthias, et al.
Publicado: (2020)

Inflammation: Bridging Age, Menopause and APOEε4 Genotype to Alzheimer’s Disease
por: Mishra, Aarti, et al.
Publicado: (2018)

Subtypes of Alzheimer's Disease Display Distinct Network Abnormalities Extending Beyond Their Pattern of Brain Atrophy
por: Ferreira, Daniel, et al.
Publicado: (2019)

The Effect of the APOE-ε4 Allele on the Cholinergic Circuitry for Subjects With Different Levels of Cognitive Impairment
por: Lai, Ying-Liang Larry, et al.
Publicado: (2021)

Effect of APOE ε4 genotype on amyloid-β and tau accumulation in Alzheimer’s disease
por: Baek, Min Seok, et al.
Publicado: (2020)

APOE ε4 genotype-dependent cerebrospinal fluid proteomic signatures in Alzheimer’s disease
por: Konijnenberg, Elles, et al.
Publicado: (2020)

A Case of Cerebral Amyloid Angiopathy-Related Inflammation With the Rare Apolipoprotein ε2/ε2 Genotype
por: Xu, Yin-Yan, et al.
Publicado: (2019)

APOE ε4/ε4 homozygotes with early Alzheimer's disease show accelerated hippocampal atrophy and cortical thinning that correlates with cognitive decline
por: Abushakra, Susan, et al.
Publicado: (2020)

APOE ε4 Is Associated with Disproportionate Progressive Hippocampal Atrophy in AD
por: Manning, Emily N., et al.
Publicado: (2014)

Brain ApoA-I, ApoJ and ApoE Immunodetection in Cerebral Amyloid Angiopathy
por: Camacho, Jessica, et al.
Publicado: (2019)

Sex-specific BDNF and APOE ε4 genotype interactions on white matter hyperintensity volume
por: Pitts, Brandon
Publicado: (2020)

Correction: APOE ε4 Is Associated with Disproportionate Progressive Hippocampal Atrophy in AD
Publicado: (2014)

Correction: APOE ε4 Is Associated with Disproportionate Progressive Hippocampal Atrophy in AD
Publicado: (2014)

Impact of APOE ε4 genotype on initial cognitive symptoms differs for Alzheimer’s and Lewy body neuropathology
por: Pillai, Jagan A., et al.
Publicado: (2021)

Rate of brain aging and APOE ε4 are synergistic risk factors for Alzheimer’s disease
por: Glorioso, Christin A, et al.
Publicado: (2019)

Sex and APOE: A memory advantage in male APOE ε4 carriers in midlife
por: Zokaei, Nahid, et al.
Publicado: (2017)

APOE-ε4 Is Associated With Reduced Verbal Memory Performance and Higher Emotional, Cognitive, and Everyday Executive Function Symptoms Two Months After Mild Traumatic Brain Injury
por: Hellstrøm, Torgeir, et al.
Publicado: (2022)

Identifying Morphological Patterns of Hippocampal Atrophy in Patients With Mesial Temporal Lobe Epilepsy and Alzheimer Disease
por: Duan, Yiran, et al.
Publicado: (2020)

Frequency of Biologically Defined Alzheimer Disease in Relation to Age, Sex, APOE ε4, and Cognitive Impairment
por: Therriault, Joseph, et al.
Publicado: (2021)

Association Between Hippocampus, Thalamus, and Caudate in Mild Cognitive Impairment APOEε4 Carriers: A Structural Covariance MRI Study
por: Novellino, Fabiana, et al.
Publicado: (2019)

Effects of sex and APOE ε4 genotype on brain mitochondrial high-energy phosphates in midlife individuals at risk for Alzheimer’s disease: A (31)Phosphorus MR spectroscopy study
por: Jett, Steven, et al.
Publicado: (2023)

The APOE(ε3/ε4) Genotype Drives Distinct Gene Signatures in the Cortex of Young Mice
por: Foley, Kate E., et al.
Publicado: (2022)

APOE genotype and Alzheimer’s immunotherapy
por: Pankiewicz, Joanna E., et al.
Publicado: (2017)

Association of APOE Serum Levels and APOE ε2, ε3, and ε4 Alleles with Optic Neuritis
por: Momkute, Liucija, et al.
Publicado: (2022)

APOE ε4, an Alzheimer’s disease susceptibility allele, and smoking cessation
por: Ashare, Rebecca L., et al.
Publicado: (2012)

Age‐dependent effects of APOE ε4 in preclinical Alzheimer's disease
por: Bonham, Luke W., et al.
Publicado: (2016)

APOEε4 and risk of Alzheimer’s disease – time to move forward
por: Lefterov, Iliya, et al.
Publicado: (2023)

Spatiotemporal Propagation of the Cortical Atrophy: Population and Individual Patterns
por: Koval, Igor, et al.
Publicado: (2018)

Sex Moderates Amyloid and Apolipoprotein ε4 Effects on Default Mode Network Connectivity at Rest
por: Caldwell, Jessica Z. K., et al.
Publicado: (2019)

Associations of the APOE ε2 and ε4 alleles and polygenic profiles comprising APOE-TOMM40-APOC1 variants with Alzheimer’s disease biomarkers
por: Kulminski, Alexander M., et al.
Publicado: (2022)

Recurrent Lobar Hemorrhages and Multiple Cortical Superficial Siderosis in a Patient of Alzheimer's Disease With Homozygous APOE ε2 Allele Presenting Hypobetalipoproteinemia and Pathological Findings of (18)F-THK5351 Positron Emission Tomography: A Case Report
por: Ikeda, Masaki, et al.
Publicado: (2021)

APOE in the bullseye of neurodegenerative diseases: impact of the APOE genotype in Alzheimer’s disease pathology and brain diseases
por: Fernández-Calle, Rosalía, et al.
Publicado: (2022)

A Biomarker for Alzheimer’s Disease Based on Patterns of Regional Brain Atrophy
por: Frenzel, Stefan, et al.
Publicado: (2020)

APOE genotype and sex affect microglial interactions with plaques in Alzheimer’s disease mice
por: Stephen, T. L., et al.
Publicado: (2019)

APOE Genotype and Alzheimer Disease Risk Across Age, Sex, and Population Ancestry
por: Belloy, Michael E., et al.
Publicado: (2023)

The APOE ε4 genotype modulates CSF YKL-40 levels and their structural brain correlates in the continuum of Alzheimer's disease but not those of sTREM2
por: Gispert, Juan Domingo, et al.
Publicado: (2016)

Sex modifies APOE ε4 dose effect on brain tau deposition in cognitively impaired individuals
por: Yan, Shaozhen, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ejpffr9bmiji71qf2hhm6fph9q