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Proteasome inhibition reduces plasma cell and antibody secretion, but not angiotensin II-induced hypertension

INTRODUCTION: Depletion of mature B cells affords protection against experimental hypertension. However, whether B cell-mediated hypertension is dependent on differentiation into antibody-secreting cells (ASCs) remains unclear. Using the proteasome inhibitor, bortezomib, the present study tested the...

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Detalles Bibliográficos
Autores principales: Figueiredo Galvao, Hericka Bruna, Dinh, Quynh Nhu, Thomas, Jordyn M., Wassef, Flavia, Diep, Henry, Bobik, Alex, Sobey, Christopher G., Drummond, Grant R., Vinh, Antony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272792/
https://www.ncbi.nlm.nih.gov/pubmed/37332591
http://dx.doi.org/10.3389/fcvm.2023.1184982

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