NF-κB fingerprinting reveals heterogeneous NF-κB composition in diffuse large B-cell lymphoma

INTRODUCTION: Improving treatments for Diffuse Large B-Cell Lymphoma (DLBCL) is challenged by the vast heterogeneity of the disease. Nuclear factor-κB (NF-κB) is frequently aberrantly activated in DLBCL. Transcriptionally active NF-κB is a dimer containing either RelA, RelB or cRel, but the variabil...

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Detalles Bibliográficos
Autores principales: Jayawant, Eleanor, Pack, Arran, Clark, Heather, Kennedy, Emma, Ghodke, Ankur, Jones, John, Pepper, Chris, Pepper, Andrea, Mitchell, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272839/
https://www.ncbi.nlm.nih.gov/pubmed/37333821
http://dx.doi.org/10.3389/fonc.2023.1181660

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