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Genomic variation during culture adaptation of genetically complex Plasmodium falciparum clinical isolates
Experimental studies on the biology of malaria parasites have mostly been based on laboratory-adapted lines, but there is limited understanding of how these may differ from parasites in natural infections. Loss-of-function mutants have previously been shown to emerge during culture of some Plasmodiu...
Autores principales: | Claessens, Antoine, Stewart, Lindsay B., Drury, Eleanor, Ahouidi, Ambroise D., Amambua-Ngwa, Alfred, Diakite, Mahamadou, Kwiatkowski, Dominic P., Awandare, Gordon A., Conway, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Microbiology Society
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272863/ https://www.ncbi.nlm.nih.gov/pubmed/37204422 http://dx.doi.org/10.1099/mgen.0.001009 |
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