Cargando…

Expression analysis of TRAF2‑ and NCK‑interacting protein kinase (TNIK) and phosphorylated TNIK in papillary thyroid carcinoma

The aim of the present study was to evaluate the expression of TRAF2- and NCK-interacting kinase (TNIK) and the levels of the active form of TNIK, phosphorylated (p)-TNIK, in papillary thyroid carcinoma (PTC), and to identify and compare the levels of TNIK and p-TNIK among PTC, benign thyroid tumors...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Jiali, Lan, Lili, Xu, Yuru, Liu, Shenghui, Liu, Meng, Hu, Guobin, Wu, Ganxun, Zhao, Yan, Shi, Jian, Wang, Jingtian, Sun, Yixin, Wang, Zhanlong, Zhao, Ruili
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2023
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272969/ https://www.ncbi.nlm.nih.gov/pubmed/37332335 http://dx.doi.org/10.3892/ol.2023.13896

Ejemplares similares

Prognostic significance of Traf2- and Nck- interacting kinase (TNIK) in colorectal cancer
por: Takahashi, Hidenori, et al.
Publicado: (2015)

Computational study on new natural compound inhibitors of Traf2 and Nck-interacting kinase (TNIK)
por: Ma, Lushun, et al.
Publicado: (2022)

Deficiency of germinal center kinase TRAF2 and NCK-interacting kinase (TNIK) in B cells does not affect atherosclerosis
por: van Os, Bram W., et al.
Publicado: (2023)

Structural Insight into TNIK Inhibition
por: Kukimoto-Niino, Mutsuko, et al.
Publicado: (2022)

Emergence of TNIK inhibitors in cancer therapeutics
por: Yamada, Tesshi, et al.
Publicado: (2017)

TNIK inhibition abrogates colorectal cancer stemness
por: Masuda, Mari, et al.
Publicado: (2016)

Direct conversion of osteosarcoma to adipocytes by targeting TNIK
por: Hirozane, Toru, et al.
Publicado: (2021)

The essential role of TNIK gene amplification in gastric cancer growth
por: Yu, D-H, et al.
Publicado: (2014)

The essential role of TNIK gene amplification in gastric cancer growth
por: Yu, D-H, et al.
Publicado: (2014)

TNIK is a conserved regulator of glucose and lipid metabolism in obesity
por: Pham, T. C. Phung, et al.
Publicado: (2023)

A Novel Aminothiazole KY-05009 with Potential to Inhibit Traf2- and Nck-Interacting Kinase (TNIK) Attenuates TGF-β1-Mediated Epithelial-to-Mesenchymal Transition in Human Lung Adenocarcinoma A549 Cells
por: Kim, Jiyeon, et al.
Publicado: (2014)

Identification of TNIK as a novel potential drug target in thyroid cancer based on protein druggability prediction
por: Yang, Yi-Fei, et al.
Publicado: (2021)

Agonistic and Antagonistic Roles for TNIK and MINK in Non-Canonical and Canonical Wnt Signalling
por: Mikryukov, Alexander, et al.
Publicado: (2012)

TNIK Inhibition Has Dual Synergistic Effects on Tumor and Associated Immune Cells
por: Kim, Jaehee, et al.
Publicado: (2022)

Rap2 and TNIK control Plexin-dependent tiled synaptic innervation in C. elegans
por: Chen, Xi, et al.
Publicado: (2018)

TNIK signaling imprints CD8(+) T cell memory formation early after priming
por: Jaeger-Ruckstuhl, Carla A., et al.
Publicado: (2020)

Characterization of the ERG-regulated Kinome in Prostate Cancer Identifies TNIK as a Potential Therapeutic Target()()
por: Lee, Rachel S, et al.
Publicado: (2019)

Molecular Docking analysis of the TNIK Receptor protein with a potential Inhibitor from the NPACT databas
por: Rosita, Arokiaraj Sherlin, et al.
Publicado: (2020)

P1343: TNIK SIGNALLING IMPAIRS SELF-RENEWAL AND LONG-TERM RECONSTITUTION CAPACITY OF HSCS
por: Palombella, Luca, et al.
Publicado: (2023)

De Novo Discovery of Thiopeptide Pseudo-natural Products Acting as Potent and Selective TNIK Kinase Inhibitors
por: Vinogradov, Alexander A., et al.
Publicado: (2022)

Disease-associated synaptic scaffold protein CNK2 modulates PSD size and influences localisation of the regulatory kinase TNIK
por: Zieger, Hanna L., et al.
Publicado: (2020)

Simultaneous CK2/TNIK/DYRK1 inhibition by 108600 suppresses triple negative breast cancer stem cells and chemotherapy-resistant disease
por: Sato, Katsutoshi, et al.
Publicado: (2021)

The Germinal Center Kinase TNIK Is Required for Canonical NF-κB and JNK Signaling in B-Cells by the EBV Oncoprotein LMP1 and the CD40 Receptor
por: Shkoda, Anna, et al.
Publicado: (2012)

Feasibility of Targeting Traf2-and-Nck-Interacting Kinase in Synovial Sarcoma
por: Sekita, Tetsuya, et al.
Publicado: (2020)

Synergistic inhibition effect of TNIK inhibitor KY-05009 and receptor tyrosine kinase inhibitor dovitinib on IL-6-induced proliferation and Wnt signaling pathway in human multiple myeloma cells
por: Lee, Yura, et al.
Publicado: (2017)

Comprehensive Modeling and Discovery of Mebendazole as a Novel TRAF2- and NCK-interacting Kinase Inhibitor
por: Tan, Zhi, et al.
Publicado: (2016)

Traf2 and NCK Interacting Kinase Is a Critical Regulator of Procollagen I Trafficking and Hepatic Fibrogenesis in Mice
por: Buchl, Samuel C., et al.
Publicado: (2021)

Nck by the numbers
por: Leslie, Mitch
Publicado: (2012)

Pharmacological blockage of transforming growth factor-β signalling by a Traf2- and Nck-interacting kinase inhibitor, NCB-0846
por: Sugano, Teppei, et al.
Publicado: (2020)

Non-overlapping functions of Nck1 and Nck2 adaptor proteins in T cell activation
por: Ngoenkam, Jatuporn, et al.
Publicado: (2014)

Distinct Requirements for Adaptor Proteins NCK1 and NCK2 in Mammary Gland Development
por: Golding, Adam P., et al.
Publicado: (2023)

Depletion of the Adaptor Protein NCK Increases UV-Induced p53 Phosphorylation and Promotes Apoptosis
por: Errington, Timothy M., et al.
Publicado: (2013)

Endothelial NCK2 promotes atherosclerosis progression in male but not female Nck1-null atheroprone mice
por: Bywaters, Briana C., et al.
Publicado: (2022)

Lack of Nck1 protein and Nck-CD3 interaction caused the increment of lipid content in Jurkat T cells
por: Nuiyen, Aussanee, et al.
Publicado: (2022)

High hsa_circ_0081621 expression indicates a poor prognosis of laryngeal squamous cell carcinoma: A bioinformatics analysis and retrospective clinical study
por: Liu, Meng, et al.
Publicado: (2023)

Genetic Alterations in Papillary Thyroid Carcinoma With Hashimoto(’)s Thyroiditis： ANK3, an Indolent Maintainer of Papillary Thyroid Carcinoma
por: Zeng, Chao, et al.
Publicado: (2022)

Alterations of Oxidative Phosphorylation Complexes in Papillary Thyroid Carcinoma
por: Zimmermann, Franz A., et al.
Publicado: (2018)

OSU-03012 sensitizes breast cancers to lapatinib-induced cell killing: a role for Nck1 but not Nck2
por: West, N Winston, et al.
Publicado: (2013)

Nck1, But Not Nck2, Mediates Disturbed Flow‐Induced p21‐Activated Kinase Activation and Endothelial Permeability
por: Alfaidi, Mabruka, et al.
Publicado: (2020)

The Nck-interacting kinase NIK increases Arp2/3 complex activity by phosphorylating the Arp2 subunit
por: LeClaire, Lawrence L., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_5h6olola3fi563q0qgcjnj5cji