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Engeletin alleviates cerebral ischemia reperfusion‐induced neuroinflammation via the HMGB1/TLR4/NF‐κB network

High‐mobility group box1 (HMGB1) induces inflammatory injury, and emerging reports suggest that it is critical for brain ischemia reperfusion. Engeletin, a natural Smilax glabra rhizomilax derivative, is reported to possess anti‐inflammatory activity. Herein, we examined the mechanism of engeletin‐m...

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Detalles Bibliográficos
Autores principales: Xu, Yangyang, Zhang, Jie, Gao, Fei, Cheng, Wenna, Zhang, Ye, Wei, Chuanmei, Zhang, Shuping, Gao, Xinfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10273068/
https://www.ncbi.nlm.nih.gov/pubmed/37132060
http://dx.doi.org/10.1111/jcmm.17758