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Combined inhibition of XIAP and autophagy induces apoptosis and differentiation in acute myeloid leukaemia

Perturbations in autophagy, apoptosis and differentiation have greatly affected the progression and therapy of acute myeloid leukaemia (AML). The role of X‐linked inhibitor of apoptosis (XIAP)‐related autophagy remains unclear in AML therapeutics. Here, we found that XIAP was highly expressed and as...

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Detalles Bibliográficos
Autores principales: Huang, Ziyang, Zhou, Jifan, Jiang, Yinyan, Han, Yixiang, Wang, Xiaofang, Li, Fanfan, Jiang, Songfu, Yu, Kang, Zhang, Shenghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10273072/
https://www.ncbi.nlm.nih.gov/pubmed/37154878
http://dx.doi.org/10.1111/jcmm.17765