A Lysosome-Targeted Tetrazine for Organelle-Specific Click-to-Release Chemistry in Antigen Presenting Cells

[Image: see text] Bioorthogonal deprotections are readily used to control biological function in a cell-specific manner. To further improve the spatial resolution of these reactions, we here present a lysosome-targeted tetrazine for an organelle-specific deprotection reaction. We show that trans-cyc...

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Detalles Bibliográficos
Autores principales: Ligthart, Nina A.M., de Geus, Mark A.R., van de Plassche, Merel A.T., Torres García, Diana, Isendoorn, Marjolein M.E., Reinalda, Luuk, Ofman, Daniëlle, van Leeuwen, Tyrza, van Kasteren, Sander I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10273227/
https://www.ncbi.nlm.nih.gov/pubmed/37269296
http://dx.doi.org/10.1021/jacs.3c02139

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