In silico clinical trial evaluating lisdexamfetamine’s and methylphenidate’s mechanism of action computational models in an attention-deficit/hyperactivity disorder virtual patients’ population

INTRODUCTION: Attention-deficit/hyperactivity disorder (ADHD) is an impairing psychiatric condition with the stimulants, lisdexamfetamine (LDX), and methylphenidate (MPH), as the first lines pharmacological treatment. METHODS: Herein, we applied a novel in silico method to evaluate virtual LDX (vLDX...

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Detalles Bibliográficos
Autores principales: Gutiérrez-Casares, José Ramón, Quintero, Javier, Segú-Vergés, Cristina, Rodríguez Monterde, Pilar, Pozo-Rubio, Tamara, Coma, Mireia, Montoto, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Psychiatry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10273406/
https://www.ncbi.nlm.nih.gov/pubmed/37333910
http://dx.doi.org/10.3389/fpsyt.2023.939650

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