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LRRC6 regulates biogenesis of motile cilia by aiding FOXJ1 translocation into the nucleus

BACKGROUND: LRRC6 is an assembly factor for dynein arms in the cytoplasm of motile ciliated cells, and when mutated, dynein arm components remained in the cytoplasm. Here, we demonstrate the role of LRRC6 in the active nuclear translocation of FOXJ1, a master regulator for cilia-associated gene tran...

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Detalles Bibliográficos
Autores principales:	Kim, Dong Yun, Sub, Yu Jin, Kim, Hye-Youn, Cho, Kyeong Jee, Choi, Won Il, Choi, Yo Jun, Lee, Min Goo, Hildebrandt, Friedhelm, Gee, Heon Yung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10273532/ https://www.ncbi.nlm.nih.gov/pubmed/37328841 http://dx.doi.org/10.1186/s12964-023-01135-y

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