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Does First-Use Syndrome Happen During Apheresis? A Case Report

Steam, dry heat, radiation, ethylene oxide gas, evaporated hydrogen peroxide, and many other sterilization methods are used to sanitize medical equipment (e.g., chlorine dioxide gas, nitrogen dioxide, and vaporized peracetic acid). The benefits of ethylene oxide (EO) are its great processing capabil...

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Detalles Bibliográficos
Autores principales: Hoque, Ashraful, Basak, Sushanta K, Al Mamun, ABM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10273777/
https://www.ncbi.nlm.nih.gov/pubmed/37332446
http://dx.doi.org/10.7759/cureus.39126
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author Hoque, Ashraful
Basak, Sushanta K
Al Mamun, ABM
author_facet Hoque, Ashraful
Basak, Sushanta K
Al Mamun, ABM
author_sort Hoque, Ashraful
collection PubMed
description Steam, dry heat, radiation, ethylene oxide gas, evaporated hydrogen peroxide, and many other sterilization methods are used to sanitize medical equipment (e.g., chlorine dioxide gas, nitrogen dioxide, and vaporized peracetic acid). The benefits of ethylene oxide (EO) are its great processing capabilities, high ionic conductivity, high flexibility, low cost, and exceptional adhesive qualities. Patients on hemodialysis, those undergoing extracorporeal photopheresis, and plasmapheresis donors have all reported allergic reactions to EO. Differentiating between IgE-mediated anaphylaxis and anaphylactoid reactions is often impossible in practice due to the wide range of clinical symptoms. The infrequency of EO reactions coupled with healthcare personnel's lack of familiarity with this clinical phenomenon may result in their underdiagnosis. We describe the case of a platelet donor who developed an allergy, while donating at a transfusion facility, due to an ethylene oxide-sterilized apheretic kit. We aim to draw attention to the fact that care should be given while handling cases of this nature as they can become life-threatening.
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spelling pubmed-102737772023-06-17 Does First-Use Syndrome Happen During Apheresis? A Case Report Hoque, Ashraful Basak, Sushanta K Al Mamun, ABM Cureus Allergy/Immunology Steam, dry heat, radiation, ethylene oxide gas, evaporated hydrogen peroxide, and many other sterilization methods are used to sanitize medical equipment (e.g., chlorine dioxide gas, nitrogen dioxide, and vaporized peracetic acid). The benefits of ethylene oxide (EO) are its great processing capabilities, high ionic conductivity, high flexibility, low cost, and exceptional adhesive qualities. Patients on hemodialysis, those undergoing extracorporeal photopheresis, and plasmapheresis donors have all reported allergic reactions to EO. Differentiating between IgE-mediated anaphylaxis and anaphylactoid reactions is often impossible in practice due to the wide range of clinical symptoms. The infrequency of EO reactions coupled with healthcare personnel's lack of familiarity with this clinical phenomenon may result in their underdiagnosis. We describe the case of a platelet donor who developed an allergy, while donating at a transfusion facility, due to an ethylene oxide-sterilized apheretic kit. We aim to draw attention to the fact that care should be given while handling cases of this nature as they can become life-threatening. Cureus 2023-05-17 /pmc/articles/PMC10273777/ /pubmed/37332446 http://dx.doi.org/10.7759/cureus.39126 Text en Copyright © 2023, Hoque et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Allergy/Immunology
Hoque, Ashraful
Basak, Sushanta K
Al Mamun, ABM
Does First-Use Syndrome Happen During Apheresis? A Case Report
title Does First-Use Syndrome Happen During Apheresis? A Case Report
title_full Does First-Use Syndrome Happen During Apheresis? A Case Report
title_fullStr Does First-Use Syndrome Happen During Apheresis? A Case Report
title_full_unstemmed Does First-Use Syndrome Happen During Apheresis? A Case Report
title_short Does First-Use Syndrome Happen During Apheresis? A Case Report
title_sort does first-use syndrome happen during apheresis? a case report
topic Allergy/Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10273777/
https://www.ncbi.nlm.nih.gov/pubmed/37332446
http://dx.doi.org/10.7759/cureus.39126
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