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EraSOR: a software tool to eliminate inflation caused by sample overlap in polygenic score analyses
BACKGROUND: Polygenic risk score (PRS) analyses are now routinely applied across biomedical research. However, as PRS studies grow in size, there is an increased risk of sample overlap between the genome-wide association study (GWAS) from which the PRS is derived and the “target sample,” in which PR...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10273836/ https://www.ncbi.nlm.nih.gov/pubmed/37326441 http://dx.doi.org/10.1093/gigascience/giad043 |