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Effect of Ajwa date pits powder (Phoenix dactylifera L.) on body composition, lipid profile and blood pressure in patients with hyperlipidemia: A randomized clinical trial
OBJECTIVE: To evaluate the effect of Ajwa dates pit powder (ADP) on lipid profile, body composition and blood pressure in patients with hyperlipidemia. MATERIALS AND METHODS: This randomized controlled clinical study was carried out on 40 patients with total cholesterol >200 mg/dl, triglycerides...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mashhad University of Medical Sciences
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274311/ https://www.ncbi.nlm.nih.gov/pubmed/37333476 http://dx.doi.org/10.22038/AJP.2022.21316 |
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author | Nasrullah, Parkha Riaz Sehar, Bismillah Safdar, Mahpara Fatima, Sadia Zeb, Falak Shah, Jahan Ali Khan Khalil, Atif Ahmed, Bilal Alsubaie, Ali Saad R. Zaman, Muhammad Haidar |
author_facet | Nasrullah, Parkha Riaz Sehar, Bismillah Safdar, Mahpara Fatima, Sadia Zeb, Falak Shah, Jahan Ali Khan Khalil, Atif Ahmed, Bilal Alsubaie, Ali Saad R. Zaman, Muhammad Haidar |
author_sort | Nasrullah, Parkha Riaz |
collection | PubMed |
description | OBJECTIVE: To evaluate the effect of Ajwa dates pit powder (ADP) on lipid profile, body composition and blood pressure in patients with hyperlipidemia. MATERIALS AND METHODS: This randomized controlled clinical study was carried out on 40 patients with total cholesterol >200 mg/dl, triglycerides >150 mg/dl and BMI >25, of either sex, aged 30-50 years, who were recruited through written consent. The patients were divided into two groups (n=20 each): the ADP and the control group (CG). All patients received the doctor’s prescribed class A statin (Rosuvastatin/ Atorvastatin) 10 mg/day, while 2.7 g ADP was given on daily basis before breakfast with lukewarm water for 40 days and the control group received the same amount of wheat flour. Body composition, blood pressure and lipid profile were determined at baseline, and after 20 and 40 days. Data were analyzed by using SPSS and GraphPad Prism. RESULTS: ADP significantly reduced body weight (p<0.001), BMI (p<0.001), fat mass, body fat percentage, visceral fat area and waist circumference compared to the control group. Similarly, ADP significantly (p=0.000) decreased the serum level of total cholesterol and low-density lipoprotein. CONCLUSION: ADP may have the potential to improve dyslipidemia and obesity. |
format | Online Article Text |
id | pubmed-10274311 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Mashhad University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-102743112023-06-17 Effect of Ajwa date pits powder (Phoenix dactylifera L.) on body composition, lipid profile and blood pressure in patients with hyperlipidemia: A randomized clinical trial Nasrullah, Parkha Riaz Sehar, Bismillah Safdar, Mahpara Fatima, Sadia Zeb, Falak Shah, Jahan Ali Khan Khalil, Atif Ahmed, Bilal Alsubaie, Ali Saad R. Zaman, Muhammad Haidar Avicenna J Phytomed Original Research OBJECTIVE: To evaluate the effect of Ajwa dates pit powder (ADP) on lipid profile, body composition and blood pressure in patients with hyperlipidemia. MATERIALS AND METHODS: This randomized controlled clinical study was carried out on 40 patients with total cholesterol >200 mg/dl, triglycerides >150 mg/dl and BMI >25, of either sex, aged 30-50 years, who were recruited through written consent. The patients were divided into two groups (n=20 each): the ADP and the control group (CG). All patients received the doctor’s prescribed class A statin (Rosuvastatin/ Atorvastatin) 10 mg/day, while 2.7 g ADP was given on daily basis before breakfast with lukewarm water for 40 days and the control group received the same amount of wheat flour. Body composition, blood pressure and lipid profile were determined at baseline, and after 20 and 40 days. Data were analyzed by using SPSS and GraphPad Prism. RESULTS: ADP significantly reduced body weight (p<0.001), BMI (p<0.001), fat mass, body fat percentage, visceral fat area and waist circumference compared to the control group. Similarly, ADP significantly (p=0.000) decreased the serum level of total cholesterol and low-density lipoprotein. CONCLUSION: ADP may have the potential to improve dyslipidemia and obesity. Mashhad University of Medical Sciences 2023 /pmc/articles/PMC10274311/ /pubmed/37333476 http://dx.doi.org/10.22038/AJP.2022.21316 Text en https://creativecommons.org/licenses/by/3.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/ (https://creativecommons.org/licenses/by/3.0/) ) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Research Nasrullah, Parkha Riaz Sehar, Bismillah Safdar, Mahpara Fatima, Sadia Zeb, Falak Shah, Jahan Ali Khan Khalil, Atif Ahmed, Bilal Alsubaie, Ali Saad R. Zaman, Muhammad Haidar Effect of Ajwa date pits powder (Phoenix dactylifera L.) on body composition, lipid profile and blood pressure in patients with hyperlipidemia: A randomized clinical trial |
title | Effect of Ajwa date pits powder (Phoenix dactylifera L.) on body composition, lipid profile and blood pressure in patients with hyperlipidemia: A randomized clinical trial |
title_full | Effect of Ajwa date pits powder (Phoenix dactylifera L.) on body composition, lipid profile and blood pressure in patients with hyperlipidemia: A randomized clinical trial |
title_fullStr | Effect of Ajwa date pits powder (Phoenix dactylifera L.) on body composition, lipid profile and blood pressure in patients with hyperlipidemia: A randomized clinical trial |
title_full_unstemmed | Effect of Ajwa date pits powder (Phoenix dactylifera L.) on body composition, lipid profile and blood pressure in patients with hyperlipidemia: A randomized clinical trial |
title_short | Effect of Ajwa date pits powder (Phoenix dactylifera L.) on body composition, lipid profile and blood pressure in patients with hyperlipidemia: A randomized clinical trial |
title_sort | effect of ajwa date pits powder (phoenix dactylifera l.) on body composition, lipid profile and blood pressure in patients with hyperlipidemia: a randomized clinical trial |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274311/ https://www.ncbi.nlm.nih.gov/pubmed/37333476 http://dx.doi.org/10.22038/AJP.2022.21316 |
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