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Effect of Ajwa date pits powder (Phoenix dactylifera L.) on body composition, lipid profile and blood pressure in patients with hyperlipidemia: A randomized clinical trial

OBJECTIVE: To evaluate the effect of Ajwa dates pit powder (ADP) on lipid profile, body composition and blood pressure in patients with hyperlipidemia. MATERIALS AND METHODS: This randomized controlled clinical study was carried out on 40 patients with total cholesterol >200 mg/dl, triglycerides...

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Autores principales: Nasrullah, Parkha Riaz, Sehar, Bismillah, Safdar, Mahpara, Fatima, Sadia, Zeb, Falak, Shah, Jahan, Ali Khan Khalil, Atif, Ahmed, Bilal, Alsubaie, Ali Saad R., Zaman, Muhammad Haidar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274311/
https://www.ncbi.nlm.nih.gov/pubmed/37333476
http://dx.doi.org/10.22038/AJP.2022.21316
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author Nasrullah, Parkha Riaz
Sehar, Bismillah
Safdar, Mahpara
Fatima, Sadia
Zeb, Falak
Shah, Jahan
Ali Khan Khalil, Atif
Ahmed, Bilal
Alsubaie, Ali Saad R.
Zaman, Muhammad Haidar
author_facet Nasrullah, Parkha Riaz
Sehar, Bismillah
Safdar, Mahpara
Fatima, Sadia
Zeb, Falak
Shah, Jahan
Ali Khan Khalil, Atif
Ahmed, Bilal
Alsubaie, Ali Saad R.
Zaman, Muhammad Haidar
author_sort Nasrullah, Parkha Riaz
collection PubMed
description OBJECTIVE: To evaluate the effect of Ajwa dates pit powder (ADP) on lipid profile, body composition and blood pressure in patients with hyperlipidemia. MATERIALS AND METHODS: This randomized controlled clinical study was carried out on 40 patients with total cholesterol >200 mg/dl, triglycerides >150 mg/dl and BMI >25, of either sex, aged 30-50 years, who were recruited through written consent. The patients were divided into two groups (n=20 each): the ADP and the control group (CG). All patients received the doctor’s prescribed class A statin (Rosuvastatin/ Atorvastatin) 10 mg/day, while 2.7 g ADP was given on daily basis before breakfast with lukewarm water for 40 days and the control group received the same amount of wheat flour. Body composition, blood pressure and lipid profile were determined at baseline, and after 20 and 40 days. Data were analyzed by using SPSS and GraphPad Prism. RESULTS: ADP significantly reduced body weight (p<0.001), BMI (p<0.001), fat mass, body fat percentage, visceral fat area and waist circumference compared to the control group. Similarly, ADP significantly (p=0.000) decreased the serum level of total cholesterol and low-density lipoprotein. CONCLUSION: ADP may have the potential to improve dyslipidemia and obesity.
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spelling pubmed-102743112023-06-17 Effect of Ajwa date pits powder (Phoenix dactylifera L.) on body composition, lipid profile and blood pressure in patients with hyperlipidemia: A randomized clinical trial Nasrullah, Parkha Riaz Sehar, Bismillah Safdar, Mahpara Fatima, Sadia Zeb, Falak Shah, Jahan Ali Khan Khalil, Atif Ahmed, Bilal Alsubaie, Ali Saad R. Zaman, Muhammad Haidar Avicenna J Phytomed Original Research OBJECTIVE: To evaluate the effect of Ajwa dates pit powder (ADP) on lipid profile, body composition and blood pressure in patients with hyperlipidemia. MATERIALS AND METHODS: This randomized controlled clinical study was carried out on 40 patients with total cholesterol >200 mg/dl, triglycerides >150 mg/dl and BMI >25, of either sex, aged 30-50 years, who were recruited through written consent. The patients were divided into two groups (n=20 each): the ADP and the control group (CG). All patients received the doctor’s prescribed class A statin (Rosuvastatin/ Atorvastatin) 10 mg/day, while 2.7 g ADP was given on daily basis before breakfast with lukewarm water for 40 days and the control group received the same amount of wheat flour. Body composition, blood pressure and lipid profile were determined at baseline, and after 20 and 40 days. Data were analyzed by using SPSS and GraphPad Prism. RESULTS: ADP significantly reduced body weight (p<0.001), BMI (p<0.001), fat mass, body fat percentage, visceral fat area and waist circumference compared to the control group. Similarly, ADP significantly (p=0.000) decreased the serum level of total cholesterol and low-density lipoprotein. CONCLUSION: ADP may have the potential to improve dyslipidemia and obesity. Mashhad University of Medical Sciences 2023 /pmc/articles/PMC10274311/ /pubmed/37333476 http://dx.doi.org/10.22038/AJP.2022.21316 Text en https://creativecommons.org/licenses/by/3.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/ (https://creativecommons.org/licenses/by/3.0/) ) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Research
Nasrullah, Parkha Riaz
Sehar, Bismillah
Safdar, Mahpara
Fatima, Sadia
Zeb, Falak
Shah, Jahan
Ali Khan Khalil, Atif
Ahmed, Bilal
Alsubaie, Ali Saad R.
Zaman, Muhammad Haidar
Effect of Ajwa date pits powder (Phoenix dactylifera L.) on body composition, lipid profile and blood pressure in patients with hyperlipidemia: A randomized clinical trial
title Effect of Ajwa date pits powder (Phoenix dactylifera L.) on body composition, lipid profile and blood pressure in patients with hyperlipidemia: A randomized clinical trial
title_full Effect of Ajwa date pits powder (Phoenix dactylifera L.) on body composition, lipid profile and blood pressure in patients with hyperlipidemia: A randomized clinical trial
title_fullStr Effect of Ajwa date pits powder (Phoenix dactylifera L.) on body composition, lipid profile and blood pressure in patients with hyperlipidemia: A randomized clinical trial
title_full_unstemmed Effect of Ajwa date pits powder (Phoenix dactylifera L.) on body composition, lipid profile and blood pressure in patients with hyperlipidemia: A randomized clinical trial
title_short Effect of Ajwa date pits powder (Phoenix dactylifera L.) on body composition, lipid profile and blood pressure in patients with hyperlipidemia: A randomized clinical trial
title_sort effect of ajwa date pits powder (phoenix dactylifera l.) on body composition, lipid profile and blood pressure in patients with hyperlipidemia: a randomized clinical trial
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274311/
https://www.ncbi.nlm.nih.gov/pubmed/37333476
http://dx.doi.org/10.22038/AJP.2022.21316
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