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Illuminating Dark Proteins using Reactome Pathways

Limited knowledge about a substantial portion of protein coding genes, known as “dark” proteins, hinders our understanding of their functions and potential therapeutic applications. To address this, we leveraged Reactome, the most comprehensive, open source, open-access pathway knowledgebase, to con...

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Detalles Bibliográficos
Autores principales: Brunson, Timothy, Sanati, Nasim, Matthews, Lisa, Haw, Robin, Beavers, Deidre, Shorser, Solomon, Sevilla, Cristoffer, Viteri, Guilherme, Conley, Patrick, Rothfels, Karen, Hermjakob, Henning, Stein, Lincoln, D’Eustachio, Peter, Wu, Guanming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274615/
https://www.ncbi.nlm.nih.gov/pubmed/37333417
http://dx.doi.org/10.1101/2023.06.05.543335