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DNA Structure Design Is Improved Using an Artificially Expanded Alphabet of Base Pairs Including Loop and Mismatch Thermodynamic Parameters

We show that in silico design of DNA secondary structures is improved by extending the base pairing alphabet beyond A-T and G-C to include the pair between 2-amino-8-(1'-β-D-2'-deoxyribofuranosyl)-imidazo-[1,2-a]-1,3,5-triazin-(8H)-4-one and 6-amino-3-(1'-β-D-2'-deoxyribofuranosy...

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Detalles Bibliográficos
Autores principales: Pham, Tuan M., Miffin, Terrel, Sun, Hongying, Sharp, Kenneth K., Wang, Xiaoyu, Zhu, Mingyi, Hoshika, Shuichi, Peterson, Raymond J., Benner, Steven A., Kahn, Jason D., Mathews, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274641/
https://www.ncbi.nlm.nih.gov/pubmed/37333404
http://dx.doi.org/10.1101/2023.06.06.543917