SMYD5 is a novel epigenetic gatekeeper of the mild hypothermia response

Organisms have homeostatic mechanisms to respond to cold temperature to ensure survival including the activation of the mammalian neuroprotective mild hypothermia response (MHR) at 32°C. We show activation of the MHR at euthermia by an FDA-approved medication Entacapone, proof-of-principle that the...

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Detalles Bibliográficos
Autores principales: Rafnsdottir, Salvor, Jang, Kijin, Halldorsdottir, Sara Tholl, Tomasdottir, Arnhildur, Vinod, Meghna, Möller, Katrin, Reynisdottir, Tinna, Atladottir, Laufey Halla, Allison, Kristin Elisabet, He, Jin, Zhang, Li, Northington, Frances J., Chavez-Valdez, Raul, Anderson, Kimberley Jade, Bjornsson, Hans Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274674/
https://www.ncbi.nlm.nih.gov/pubmed/37333301
http://dx.doi.org/10.1101/2023.05.11.540170

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