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Calretinin-expressing islet cells: a source of pre- and post-synaptic inhibition of non-peptidergic nociceptor input to the mouse spinal cord

Unmyelinated non-peptidergic nociceptors (NP afferents) arborise in lamina II of the spinal cord and receive GABAergic axoaxonic synapses, which mediate presynaptic inhibition. However, until now the source of this axoaxonic synaptic input was not known. Here we provide evidence that it originates f...

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Detalles Bibliográficos
Autores principales: Davis, Olivia C., Dickie, Allen C., Mustapa, Marami B., Boyle, Kieran A., Browne, Tyler J., Gradwell, Mark A., Smith, Kelly M., Polgár, Erika, Bell, Andrew M., Kókai, Éva, Watanabe, Masahiko, Wildner, Hendrik, Zeilhofer, Hanns Ulrich, Ginty, David D., Callister, Robert J., Graham, Brett A., Todd, Andrew J., Hughes, David I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274676/
https://www.ncbi.nlm.nih.gov/pubmed/37333120
http://dx.doi.org/10.1101/2023.06.01.543241