EZH2 inhibition promotes tumor immunogenicity in lung squamous cell carcinomas

Two important factors that contribute to resistance to immune checkpoint inhibitors (ICIs) are an immune-suppressive microenvironment and limited antigen presentation by tumor cells. In this study, we examine if inhibition of the methyltransferase EZH2 can increase ICI response in lung squamous cell...

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Detalles Bibliográficos
Autores principales: DuCote, Tanner J., Song, Xiulong, Naughton, Kassandra J., Chen, Fan, Plaugher, Daniel R., Childress, Avery R., Edgin, Abigail R., Qu, Xufeng, Liu, Jinze, Liu, Jinpeng, Li, Fei, Wong, Kwok-Kin, Brainson, Christine F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274685/
https://www.ncbi.nlm.nih.gov/pubmed/37333199
http://dx.doi.org/10.1101/2023.06.06.543919

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