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Recording morphogen signals reveals origins of gastruloid symmetry breaking
When cultured in three dimensional spheroids, mammalian stem cells can reproducibly self-organize a single anterior-posterior axis and sequentially differentiate into structures resembling the primitive streak and tailbud. Whereas the embryo’s body axes are instructed by spatially patterned extra-em...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274695/ https://www.ncbi.nlm.nih.gov/pubmed/37333235 http://dx.doi.org/10.1101/2023.06.02.543474 |