Differential dynamics specify MeCP2 function at methylated DNA and nucleosomes

Methyl-CpG-binding protein 2 (MeCP2) is an essential chromatin-binding protein whose mutations cause Rett syndrome (RTT), a leading cause of monogenic intellectual disabilities in females. Despite its significant biomedical relevance, the mechanism by which MeCP2 navigates the chromatin epigenetic l...

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Detalles Bibliográficos
Autores principales: Chua, Gabriella N. L., Watters, John W., Olinares, Paul Dominic B., Luo, Joshua A., Chait, Brian T., Liu, Shixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274721/
https://www.ncbi.nlm.nih.gov/pubmed/37333354
http://dx.doi.org/10.1101/2023.06.02.543478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274721/
https://www.ncbi.nlm.nih.gov/pubmed/37333354
http://dx.doi.org/10.1101/2023.06.02.543478

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