The PMA Phorbol Ester Tumor Promoter Increases Canonical Wnt Signaling Via Macropinocytosis

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Activation of the Wnt pathway lies at the core of many human cancers. Wnt and macropinocytosis are often active in the same processes, and understanding how Wnt signaling and membrane trafficking cooperate should improve our understanding of embryonic development and cancer. Here we show that a macr...

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Detalles Bibliográficos
Autores principales: Tejeda-Muñoz, Nydia, Azbazdar, Yagmur, Monka, Julia, Binder, Grace, Dayrit, Alex, Ayala, Raul, O’Brien, Neil, De Robertis, Edward M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274750/
https://www.ncbi.nlm.nih.gov/pubmed/37333286
http://dx.doi.org/10.1101/2023.06.02.543509
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