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The consequences of tetraploidy on Caenorhabditis elegans physiology and sensitivity to chemotherapeutics

Polyploid cells contain more than two copies of each chromosome. Polyploidy has important roles in development, evolution, and tissue regeneration/repair, and can arise as a programmed polyploidization event or be triggered by stress. Cancer cells are often polyploid. C. elegans nematodes are typica...

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Detalles Bibliográficos
Autores principales: Misare, Kelly R., Ampolini, Elizabeth A., Gonzalez, Hyland C., Sullivan, Kaitlan A., Li, Xin, Miller, Camille, Sosseh, Bintou, Dunne, Jaclyn B., Voelkel-Johnson, Christina, Gordon, Kacy L., Hartman, Jessica H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274754/
https://www.ncbi.nlm.nih.gov/pubmed/37333126
http://dx.doi.org/10.1101/2023.06.06.543785