Cargando…

The aryl hydrocarbon receptor regulates epidermal differentiation through transient activation of TFAP2A

The aryl hydrocarbon receptor (AHR) is an evolutionary conserved environmental sensor identified as indispensable regulator of epithelial homeostasis and barrier organ function. Molecular signaling cascade and target genes upon AHR activation and their contribution to cell and tissue function are ho...

Descripción completa

Detalles Bibliográficos
Autores principales:	Smits, Jos P.H., Qu, Jieqiong, Pardow, Felicitas, van den Brink, Noa J.M., Rodijk-Olthuis, Diana, van Vlijmen-Willems, Ivonne M.J.J., van Heeringen, Simon J., Zeeuwen, Patrick L.J.M., Schalkwijk, Joost, Zhou, Huiqing, van den Bogaard, Ellen H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274772/ https://www.ncbi.nlm.nih.gov/pubmed/37333234 http://dx.doi.org/10.1101/2023.06.07.544032

Ejemplares similares

Identification of Keratinocyte Mitogens: Implications for Hyperproliferation in Psoriasis and Atopic Dermatitis
por: Niehues, Hanna, et al.
Publicado: (2021)

Novel methodologies for host-microbe interactions and microbiome-targeted therapeutics in 3D organotypic skin models
por: Rikken, Gijs, et al.
Publicado: (2023)

OR5-002 – In vitro studies in Schnitzler’s syndrome
por: De Koning, HD, et al.
Publicado: (2013)

Know your enemy: Unexpected, pervasive and persistent viral and bacterial contamination of primary cell cultures
por: Niehues, Hanna, et al.
Publicado: (2020)

CRISPR-Cas9‒Based Genomic Engineering in Keratinocytes: From Technology to Application
por: Smits, Jos P.H., et al.
Publicado: (2021)

Immortalized N/TERT keratinocytes as an alternative cell source in 3D human epidermal models
por: Smits, Jos P. H., et al.
Publicado: (2017)

Carboxamide Derivatives Are Potential Therapeutic AHR Ligands for Restoring IL-4 Mediated Repression of Epidermal Differentiation Proteins
por: Rikken, Gijs, et al.
Publicado: (2022)

β-Defensin-2 Protein Is a Serum Biomarker for Disease Activity in Psoriasis and Reaches Biologically Relevant Concentrations in Lesional Skin
por: Jansen, Patrick A. M., et al.
Publicado: (2009)

Genetically Programmed Differences in Epidermal Host Defense between Psoriasis and Atopic Dermatitis Patients
por: Zeeuwen, Patrick L. J. M., et al.
Publicado: (2008)

Deficiency of the human cysteine protease inhibitor cystatin M/E causes hypotrichosis and dry skin
por: van den Bogaard, Ellen H. J., et al.
Publicado: (2018)

Terminal keratinocyte differentiation in vitro is associated with a stable DNA methylome
por: Smits, Jos P. H., et al.
Publicado: (2020)

Skin microbiota in health and disease: From sequencing to biology
por: Ederveen, Thomas H. A., et al.
Publicado: (2020)

Microbiome dynamics of human epidermis following skin barrier disruption
por: Zeeuwen, Patrick LJM, et al.
Publicado: (2012)

A generic workflow for Single Locus Sequence Typing (SLST) design and subspecies characterization of microbiota
por: Ederveen, Thomas H. A., et al.
Publicado: (2019)

Cathepsin B as a potential cystatin M/E target in the mouse hair follicle
por: Oortveld, Merel A. W., et al.
Publicado: (2017)

Vesicular hand eczema transcriptome analysis provides insights into its pathophysiology
por: Voorberg, Angelique N., et al.
Publicado: (2021)

Analysis of obstetric complications and uterine connective tissue in tenascin-X-deficient humans and mice
por: Egging, David F., et al.
Publicado: (2008)

Transcription factor p63 bookmarks and regulates dynamic enhancers during epidermal differentiation
por: Kouwenhoven, Evelyn N, et al.
Publicado: (2015)

Challenges in Noninvasive Skin Biomarker Measurements in Daily Practice: A Longitudinal Study on Skin Surface Protein Detection by the Transdermal Analysis Patch in Pediatric Psoriasis
por: Schaap, Mirjam J., et al.
Publicado: (2022)

TFAP2 paralogs regulate melanocyte differentiation in parallel with MITF
por: Seberg, Hannah E., et al.
Publicado: (2017)

PW03-007 - NLRP3 genetic variants in Schnitzler’s syndrome
por: De Koning, HD, et al.
Publicado: (2013)

A molecular signature of epithelial host defense: comparative gene expression analysis of cultured bronchial epithelial cells and keratinocytes
por: Vos, Joost B, et al.
Publicado: (2006)

Accurate, high-throughput typing of copy number variation using paralogue ratios from dispersed repeats
por: Armour, John A. L., et al.
Publicado: (2007)

TFAP2 paralogs regulate midfacial development in part through a conserved ALX genetic pathway
por: Nguyen, Timothy T, et al.
Publicado: (2023)

Distinct Activities of Tfap2A and Tfap2B in the Specification of GABAergic Interneurons in the Developing Cerebellum
por: Zainolabidin, Norliyana, et al.
Publicado: (2017)

Functional Divergence of Mammalian TFAP2a and TFAP2b Transcription Factors for Bidirectional Sleep Control
por: Hu, Yang, et al.
Publicado: (2020)

TFAP2 paralogs facilitate chromatin access for MITF at pigmentation and cell proliferation genes
por: Kenny, Colin, et al.
Publicado: (2022)

Identification of functional TFAP2A and SP1 binding sites in new TFAP2A-modulated genes
por: Orso, Francesca, et al.
Publicado: (2010)

The origin of the Canary Island Seamount Province - New ages of old seamounts
por: van den Bogaard, Paul
Publicado: (2013)

Ruthenium Oxide Nanorods as Potentiometric pH Sensor for Organs-On-Chip Purposes
por: Tanumihardja, Esther, et al.
Publicado: (2018)

TfAP-2 is required for night sleep in Drosophila
por: Kucherenko, Mariya M., et al.
Publicado: (2016)

Visualisation of microvascular flow in benign uterine disorders: a pilot study of a new diagnostic technique
por: Frijlingh, M, et al.
Publicado: (2023)

TFAP2B mutation and dental anomalies
por: Tanasubsinn, Natchaya, et al.
Publicado: (2017)

Genetic and pharmacological analysis identifies a physiological role for the AHR in epidermal differentiation
por: van den Bogaard, Ellen, et al.
Publicado: (2015)

TFAP2B Haploinsufficiency Impacts Gastrointestinal Function and Leads to Pediatric Intestinal Pseudo-obstruction
por: Zada, Almira, et al.
Publicado: (2022)

A Training Course for Psychologists: Learning to Assess (Alleged) Sexual Abuse Among Victims and Perpetrators Who Have Intellectual Disabilities
por: Embregts, Petri J. C. M., et al.
Publicado: (2017)

TFAP2C regulates transcription in human naive pluripotency by opening enhancers
por: Pastor, William A., et al.
Publicado: (2018)

Deletion of the transcriptional regulator TFAP4 accelerates c-MYC-driven lymphomagenesis
por: Potts, Margaret A., et al.
Publicado: (2023)

TFAP2C Governs the Luminal Epithelial Phenotype in Mammary Development and Carcinogenesis
por: Cyr, Anthony R, et al.
Publicado: (2014)

Calcitonin gene-related peptide (receptor) antibodies: an exciting avenue for migraine treatment
por: MaassenVanDenBrink, Antoinette, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_vd1luk8opjdiulegtbb6e5p12f