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Molecular imaging with aquaporin-based reporter genes: quantitative considerations from Monte Carlo diffusion simulations
Aquaporins provide a new class of genetic tools for imaging molecular activity in deep tissues by increasing the rate of cellular water diffusion, which generates magnetic resonance contrast. However, distinguishing aquaporin contrast from the tissue background is challenging because water diffusion...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274877/ https://www.ncbi.nlm.nih.gov/pubmed/37333205 http://dx.doi.org/10.1101/2023.06.09.544324 |