(13)C metabolite tracing reveals glutamine and acetate as critical in vivo fuels for CD8(+) T cells

Infusion of 13C-labeled metabolites provides a gold-standard for understanding the metabolic processes used by T cells during immune responses in vivo. Through infusion of 13C-labeled metabolites (glucose, glutamine, acetate) in Listeria monocytogenes (Lm)-infected mice, we demonstrate that CD8+ T e...

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Detalles Bibliográficos
Autores principales: Ma, Eric H., Dahabieh, Michael S., DeCamp, Lisa M., Kaymak, Irem, Kitchen-Goosen, Susan M., Roy, Dominic G., Verway, Mark J., Johnson, Radia M., Samborska, Bozena, Scullion, Catherine A., Steadman, Mya, Vos, Matthew, Roddy, Thomas P., Krawczyk, Connie M., Williams, Kelsey S., Sheldon, Ryan D., Jones, Russell G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274878/
https://www.ncbi.nlm.nih.gov/pubmed/37333111
http://dx.doi.org/10.1101/2023.06.09.544407

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