Genetically engineering endothelial niche in human kidney organoids enables multilineage maturation, vascularization and de novo cell types

Vascularization plays a critical role in organ maturation and cell type development. Drug discovery, organ mimicry, and ultimately transplantation in a clinical setting thereby hinges on achieving robust vascularization of in vitro engineered organs. Here, focusing on human kidney organoids, we over...

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Detalles Bibliográficos
Autores principales: Maggiore, Joseph C., LeGraw, Ryan, Przepiorski, Aneta, Velazquez, Jeremy, Chaney, Christopher, Streeter, Evan, Silva-Barbosa, Anne, Franks, Jonathan, Hislop, Joshua, Hill, Alex, Wu, Haojia, Pfister, Katherine, Howden, Sara E., Watkins, Simon C., Little, Melissa, Humphreys, Benjamin D., Watson, Alan, Stolz, Donna B., Kiani, Samira, Davidson, Alan J., Carroll, Thomas J., Cleaver, Ondine, Sims-Lucas, Sunder, Ebrahimkhani, Mo R., Hukriede, Neil A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274893/
https://www.ncbi.nlm.nih.gov/pubmed/37333155
http://dx.doi.org/10.1101/2023.05.30.542848

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