Ebola Virus NP Binding to Host Protein Phosphatase-1 Regulates Capsid Formation

The Ebola virus (EBOV) transcriptional regulation involves host protein phosphatases PP1 and PP2A, which dephosphorylate the transcriptional cofactor of EBOV polymerase VP30. The 1E7–03 compound, which targets PP1, induces VP30 phosphorylation and inhibits EBOV infection. This study aimed to investi...

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Detalles Bibliográficos
Autores principales: Ahmad, Asrar, Tigabu, Bersabeh, Ivanov, Andrey, Jerebtsova, Marina, Ammosova, Tatiana, Ramanathan, Palaniappan, Kumari, Namita, Brantner, Christine A., Pietzsch, Colette A., Abdullah, Ghadeer, Popratiloff, Anastas, Widen, Steve, Bukreyev, Alexander, Nekhai, Sergei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274954/
https://www.ncbi.nlm.nih.gov/pubmed/37333330
http://dx.doi.org/10.21203/rs.3.rs-2963943/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274954/
https://www.ncbi.nlm.nih.gov/pubmed/37333330
http://dx.doi.org/10.21203/rs.3.rs-2963943/v1

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