Cargando…
Identifying modifiable comorbidities of schizophrenia by integrating electronic health records and polygenic risk
Patients with schizophrenia have substantial comorbidity contributing to reduced life expectancy of 10–20 years. Identifying which comorbidities might be modifiable could improve rates of premature mortality in this population. We hypothesize that conditions that frequently co-occur but lack shared...
Autores principales: | Vessels, Tess, Strayer, Nicholas, Choi, Karmel W., Lee, Hyunjoon, Zhang, Siwei, Han, Lide, Morley, Theodore J., Smoller, Jordan W., Xu, Yaomin, Ruderfer, Douglas M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274978/ https://www.ncbi.nlm.nih.gov/pubmed/37333378 http://dx.doi.org/10.1101/2023.06.01.23290057 |
Ejemplares similares
-
Evaluating the impact of modeling choices on the performance of integrated genetic and clinical models
por: Morley, Theodore J., et al.
Publicado: (2023) -
PheMIME: An Interactive Web App and Knowledge Base for Phenome-Wide, Multi-Institutional Multimorbidity Analysis
por: Zhang, Siwei, et al.
Publicado: (2023) -
Association Between Psychiatric Polygenic Scores, Healthcare Utilization and Comorbidity Burden
por: Kirchner, H. Lester, et al.
Publicado: (2023) -
Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia
por: Ruderfer, Douglas M., et al.
Publicado: (2013) -
Clinical laboratory test-wide association scan of polygenic scores identifies biomarkers of complex disease
por: Dennis, Jessica K., et al.
Publicado: (2021)