Intrahepatic transcriptomics differentiate advanced fibrosis and clinical outcomes in adults with the Fontan circulation

BACKGROUND: The molecular mechanisms underlying Fontan associated liver disease (FALD) remain largely unknown. We aimed to assess intrahepatic transcriptomic differences among patients with FALD according to the degree of liver fibrosis and clinical outcomes. METHODS: This retrospective cohort study...

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Detalles Bibliográficos
Autores principales: Bravo-Jaimes, Katia, Wu, Xiuju, Reardon, Leigh C, Lluri, Gentian, Lin, Jeannette P, Moore, Jeremy P, Arsdell, Glen Van, Biniwale, Reshma, Si, Ming-Sing, Naini, Bita V, Venick, Robert, Saab, Sammy, Wray, Christopher L, Ponder, Reid, Rosenthal, Carl, Klomhaus, Alexandra, Böstrom, Kristina I, Aboulhosn, Jamil A, Kaldas, Fady M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274997/
https://www.ncbi.nlm.nih.gov/pubmed/37333414
http://dx.doi.org/10.1101/2023.06.05.23290997

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