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Prevalence of pediatric lower urinary tract symptoms in a US population seeking medical care, 2003- 2014
BACKGROUND: We conducted this study to estimate the prevalence of pediatric lower urinary tract symptoms (pLUTS) in a US privately-insured pediatric population who are 18 years of age or older by age, sex, race/ethnicity from 2003–2014. This has not been previously described in the literature. METHO...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275036/ https://www.ncbi.nlm.nih.gov/pubmed/37333169 http://dx.doi.org/10.21203/rs.3.rs-2883579/v1 |
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author | Kan, Kathleen M. Agrawal, Gunjan Brosula, Raphael Venkatapuram, Pranaya Chen, Abby L. Zhang, Chiyuan A. |
author_facet | Kan, Kathleen M. Agrawal, Gunjan Brosula, Raphael Venkatapuram, Pranaya Chen, Abby L. Zhang, Chiyuan A. |
author_sort | Kan, Kathleen M. |
collection | PubMed |
description | BACKGROUND: We conducted this study to estimate the prevalence of pediatric lower urinary tract symptoms (pLUTS) in a US privately-insured pediatric population who are 18 years of age or older by age, sex, race/ethnicity from 2003–2014. This has not been previously described in the literature. METHODS: We retrospectively reviewed Optum’s de-identifed Clinformatics(®) Data Mart Database database between 2003–2014. A pLUTS patient was defined by the presence of ≥ 1 pLUTS-related ICD-9 diagnosis code between the age of 6–20 years. Neurogenic bladder, renal transplant and structural urologic disease diagnoses were excluded. Prevalence by year was calculated as a proportion of pLUTS patients among the total population at risk. Variables reviewed included age, sex, race, geographic region, household factors and clinical comorbidities including attention-deficit/hyperactivity disorder (ADHD), constipation, and sleep apnea. Point of service (POS) was calculated as a proportion of pLUTS-related claims associated with a POS compared to the total claims at all POS in the time period. RESULTS: We identified 282,427 unique patients with ≥ 1 claim for pLUTS between the ages of 6–20 years from 2003–2014. Average prevalence during this period was 0.92%, increasing from 0.63% in 2003 to 1.13% in 2014. Mean age was 12.15 years. More patients were female (59.80%), white (65.97%), between 6–10 years old (52.18%) and resided in the Southern US (44.97%). Within a single household, 81.71% reported ≤ 2 children, and 65.53% reported ≥ 3 adults. 16.88% had a diagnosis of ADHD, 19.49% had a diagnosis of constipation and 3.04% had a diagnosis of sleep apnea. 75% of pLUTS-related claims were recorded in an outpatient setting. CONCLUSIONS: Families consistently seek medical care in the outpatient setting for pLUTS. The demographic and clinical characteristics of our cohort reflect prior literature. Future studies can help define temporal relationships between household factors and onset of disease as well as characterize pLUTS-related healthcare resource utilization. Additional work is required in publicly-insured populations. |
format | Online Article Text |
id | pubmed-10275036 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | American Journal Experts |
record_format | MEDLINE/PubMed |
spelling | pubmed-102750362023-06-17 Prevalence of pediatric lower urinary tract symptoms in a US population seeking medical care, 2003- 2014 Kan, Kathleen M. Agrawal, Gunjan Brosula, Raphael Venkatapuram, Pranaya Chen, Abby L. Zhang, Chiyuan A. Res Sq Article BACKGROUND: We conducted this study to estimate the prevalence of pediatric lower urinary tract symptoms (pLUTS) in a US privately-insured pediatric population who are 18 years of age or older by age, sex, race/ethnicity from 2003–2014. This has not been previously described in the literature. METHODS: We retrospectively reviewed Optum’s de-identifed Clinformatics(®) Data Mart Database database between 2003–2014. A pLUTS patient was defined by the presence of ≥ 1 pLUTS-related ICD-9 diagnosis code between the age of 6–20 years. Neurogenic bladder, renal transplant and structural urologic disease diagnoses were excluded. Prevalence by year was calculated as a proportion of pLUTS patients among the total population at risk. Variables reviewed included age, sex, race, geographic region, household factors and clinical comorbidities including attention-deficit/hyperactivity disorder (ADHD), constipation, and sleep apnea. Point of service (POS) was calculated as a proportion of pLUTS-related claims associated with a POS compared to the total claims at all POS in the time period. RESULTS: We identified 282,427 unique patients with ≥ 1 claim for pLUTS between the ages of 6–20 years from 2003–2014. Average prevalence during this period was 0.92%, increasing from 0.63% in 2003 to 1.13% in 2014. Mean age was 12.15 years. More patients were female (59.80%), white (65.97%), between 6–10 years old (52.18%) and resided in the Southern US (44.97%). Within a single household, 81.71% reported ≤ 2 children, and 65.53% reported ≥ 3 adults. 16.88% had a diagnosis of ADHD, 19.49% had a diagnosis of constipation and 3.04% had a diagnosis of sleep apnea. 75% of pLUTS-related claims were recorded in an outpatient setting. CONCLUSIONS: Families consistently seek medical care in the outpatient setting for pLUTS. The demographic and clinical characteristics of our cohort reflect prior literature. Future studies can help define temporal relationships between household factors and onset of disease as well as characterize pLUTS-related healthcare resource utilization. Additional work is required in publicly-insured populations. American Journal Experts 2023-06-05 /pmc/articles/PMC10275036/ /pubmed/37333169 http://dx.doi.org/10.21203/rs.3.rs-2883579/v1 Text en https://creativecommons.org/licenses/by/4.0/This work is licensed under a Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/) , which allows reusers to distribute, remix, adapt, and build upon the material in any medium or format, so long as attribution is given to the creator. The license allows for commercial use. |
spellingShingle | Article Kan, Kathleen M. Agrawal, Gunjan Brosula, Raphael Venkatapuram, Pranaya Chen, Abby L. Zhang, Chiyuan A. Prevalence of pediatric lower urinary tract symptoms in a US population seeking medical care, 2003- 2014 |
title | Prevalence of pediatric lower urinary tract symptoms in a US population seeking medical care, 2003- 2014 |
title_full | Prevalence of pediatric lower urinary tract symptoms in a US population seeking medical care, 2003- 2014 |
title_fullStr | Prevalence of pediatric lower urinary tract symptoms in a US population seeking medical care, 2003- 2014 |
title_full_unstemmed | Prevalence of pediatric lower urinary tract symptoms in a US population seeking medical care, 2003- 2014 |
title_short | Prevalence of pediatric lower urinary tract symptoms in a US population seeking medical care, 2003- 2014 |
title_sort | prevalence of pediatric lower urinary tract symptoms in a us population seeking medical care, 2003- 2014 |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275036/ https://www.ncbi.nlm.nih.gov/pubmed/37333169 http://dx.doi.org/10.21203/rs.3.rs-2883579/v1 |
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