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A first-generation genome-wide map of correlated DNA methylation demonstrates highly coordinated and tissue-independent clustering across regulatory regions

Genome-wide DNA methylation studies have typically focused on quantitative assessments of CpG methylation at individual loci. Although methylation states at nearby CpG sites are known to be highly correlated, suggestive of an underlying coordinated regulatory network, the extent and consistency of i...

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Detalles Bibliográficos
Autores principales: Jajoo, Aarti, Hirschi, Owen, Schulze, Katharina, Guan, Yongtao, Hanchard, Neil A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275061/
https://www.ncbi.nlm.nih.gov/pubmed/37333260
http://dx.doi.org/10.21203/rs.3.rs-2852818/v1