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A first-generation genome-wide map of correlated DNA methylation demonstrates highly coordinated and tissue-independent clustering across regulatory regions
Genome-wide DNA methylation studies have typically focused on quantitative assessments of CpG methylation at individual loci. Although methylation states at nearby CpG sites are known to be highly correlated, suggestive of an underlying coordinated regulatory network, the extent and consistency of i...
Autores principales: | Jajoo, Aarti, Hirschi, Owen, Schulze, Katharina, Guan, Yongtao, Hanchard, Neil A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275061/ https://www.ncbi.nlm.nih.gov/pubmed/37333260 http://dx.doi.org/10.21203/rs.3.rs-2852818/v1 |
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