Deep Brain Stimulation for the Treatment of Hemichorea: Case Series and Literature Review

BACKGROUND: Hemichorea (HC) and its severe form hemiballismus (HB) are rare movement disorders which can be medically refractory to treatments and may need surgical intervention. CASE REPORT: We report 3 patients with HC-HB who had meaningful clinical improvement with unilateral deep brain stimulati...

Descripción completa

Detalles Bibliográficos
Autores principales: Masood, Zihan, Domino, Joseph S., Gragg, Antonia, Burchiel, Kim, Kinsman, Michael, Sharma, Vibhash D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ubiquity Press 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275341/
https://www.ncbi.nlm.nih.gov/pubmed/37332655
http://dx.doi.org/10.5334/tohm.765
Descripción
Sumario:BACKGROUND: Hemichorea (HC) and its severe form hemiballismus (HB) are rare movement disorders which can be medically refractory to treatments and may need surgical intervention. CASE REPORT: We report 3 patients with HC-HB who had meaningful clinical improvement with unilateral deep brain stimulation (DBS) of the globus pallidus interna (GPi). We identified 8 prior cases of HC-HB treated with GPi-DBS, and a majority of these patients experienced significant improvement in their symptoms. DISCUSSION: GPi-DBS can be considered in medically refractory HC-HB in carefully selected patients. However, data is limited to small case series and further studies are needed.

Ejemplares similares