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Noncanonical Activity of Tissue Inhibitor of Metalloproteinases 2 (TIMP2) Improves Cognition and Synapse Density in Aging

Peripheral administration of tissue inhibitor of metalloproteinases 2 (TIMP2), a protein inhibitor of matrix metalloproteinases (MMPs), has previously been shown to have beneficial effects on cognition and neurons in aged mice. Here, to better understand the potential of recombinant TIMP2 proteins,...

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Detalles Bibliográficos
Autores principales:	Britton, Rachel, Wasley, Tristan, Harish, Reema, Holz, Charles, Hall, John, Yee, Dennis C., Melton Witt, Jody, Booth, Elizabeth A., Braithwaite, Steven, Czirr, Eva, Kerrisk Campbell, Meghan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society for Neuroscience 2023
Materias:	Research Article: Confirmation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275401/ https://www.ncbi.nlm.nih.gov/pubmed/37321845 http://dx.doi.org/10.1523/ENEURO.0031-23.2023

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