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Cell competition for neuron-derived trophic factor controls the turnover and lifespan of microglia

Microglia are brain-resident macrophages capable of long-term maintenance through self-renewal. Yet the mechanism governing the turnover and lifespan of microglia remains unknown. In zebrafish, microglia arise from two sources, rostral blood island (RBI) and aorta-gonad-mesonephros (AGM). The RBI-de...

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Detalles Bibliográficos
Autores principales:	Yu, Tao, Kuang, Haoyue, Wu, Xiaohai, Huang, Ying, Wang, Jianzhong, Wen, Zilong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2023
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275588/ https://www.ncbi.nlm.nih.gov/pubmed/37327343 http://dx.doi.org/10.1126/sciadv.adf9790

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