Identification of a humanized mouse model for functional testing of immune-mediated biomaterial foreign body response

Biomedical devices comprise a major component of modern medicine, however immune-mediated fibrosis and rejection can limit their function over time. Here, we describe a humanized mouse model that recapitulates fibrosis following biomaterial implantation. Cellular and cytokine responses to multiple b...

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Detalles Bibliográficos
Autores principales: Doloff, Joshua C., Ma, Minglin, Sadraei, Atieh, Tam, Hok Hei, Farah, Shady, Hollister-Lock, Jennifer, Vegas, Arturo J., Veiseh, Omid, Quiroz, Victor M., Rakoski, Amanda, Aresta-DaSilva, Stephanie, Bader, Andrew R., Griffin, Marissa, Weir, Gordon C., Brehm, Michael A., Shultz, Leonard D., Langer, Robert, Greiner, Dale L., Anderson, Daniel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275594/
https://www.ncbi.nlm.nih.gov/pubmed/37327334
http://dx.doi.org/10.1126/sciadv.ade9488

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