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Modes of Selection in Tumors as Reflected by Two Mathematical Models and Site Frequency Spectra
The tug-of-war model was developed in a series of papers of McFarland and co-authors to account for existence of mutually counteracting rare advantageous driver mutations and more frequent slightly deleterious passenger mutations in cancer. In its original version, it was a state-dependent branching...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275603/ https://www.ncbi.nlm.nih.gov/pubmed/37333691 http://dx.doi.org/10.3389/fevo.2022.889438 |