The Uso1 globular head interacts with SNAREs to maintain viability even in the absence of the coiled-coil domain

Uso1/p115 and RAB1 tether ER-derived vesicles to the Golgi. Uso1/p115 contains a globular-head-domain (GHD), a coiled-coil (CC) mediating dimerization/tethering, and a C-terminal region (CTR) interacting with golgins. Uso1/p115 is recruited to vesicles by RAB1. Genetic studies placed Uso1 paradoxica...

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Detalles Bibliográficos
Autores principales: Bravo-Plaza, Ignacio, Tagua, Victor G, Arst, Herbert N, Alonso, Ana, Pinar, Mario, Monterroso, Begoña, Galindo, Antonio, Peñalva, Miguel A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275640/
https://www.ncbi.nlm.nih.gov/pubmed/37249218
http://dx.doi.org/10.7554/eLife.85079

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