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Non-typeable Haemophilus influenzae Osteomyelitis and Discitis of the Cervical Vertebrae in an Elderly Adult: A Case Report and Literature Review
While Haemophilus influenzae type B (Hib) is well described in the literature to cause osteomyelitis, non-typeable H. influenzae has not. In areas where vaccination is routine, the prevalence of Hib has declined, whereas, in contrast, the prevalence of non-typeable H. influenza has increased. Genera...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275657/ https://www.ncbi.nlm.nih.gov/pubmed/37332474 http://dx.doi.org/10.7759/cureus.39155 |
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author | Fong, Jing Hong Menon, Shalisha Joy Jones, Gareth Iestyn Robert Karunaratne, Hettiyadura Apsara Surangani Mendis |
author_facet | Fong, Jing Hong Menon, Shalisha Joy Jones, Gareth Iestyn Robert Karunaratne, Hettiyadura Apsara Surangani Mendis |
author_sort | Fong, Jing Hong |
collection | PubMed |
description | While Haemophilus influenzae type B (Hib) is well described in the literature to cause osteomyelitis, non-typeable H. influenzae has not. In areas where vaccination is routine, the prevalence of Hib has declined, whereas, in contrast, the prevalence of non-typeable H. influenza has increased. Generally, the non-typeable strains are less invasive but can access the vascular system by transmural migration through epithelial tight junctions or by an independent intercellular mechanism. Herein, we described a case of a 79-year-old man with the first case of non-typeable H. influenzae causing cervical osteomyelitis with associated bacteremia in an elderly adult. |
format | Online Article Text |
id | pubmed-10275657 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-102756572023-06-17 Non-typeable Haemophilus influenzae Osteomyelitis and Discitis of the Cervical Vertebrae in an Elderly Adult: A Case Report and Literature Review Fong, Jing Hong Menon, Shalisha Joy Jones, Gareth Iestyn Robert Karunaratne, Hettiyadura Apsara Surangani Mendis Cureus Internal Medicine While Haemophilus influenzae type B (Hib) is well described in the literature to cause osteomyelitis, non-typeable H. influenzae has not. In areas where vaccination is routine, the prevalence of Hib has declined, whereas, in contrast, the prevalence of non-typeable H. influenza has increased. Generally, the non-typeable strains are less invasive but can access the vascular system by transmural migration through epithelial tight junctions or by an independent intercellular mechanism. Herein, we described a case of a 79-year-old man with the first case of non-typeable H. influenzae causing cervical osteomyelitis with associated bacteremia in an elderly adult. Cureus 2023-05-17 /pmc/articles/PMC10275657/ /pubmed/37332474 http://dx.doi.org/10.7759/cureus.39155 Text en Copyright © 2023, Fong et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Internal Medicine Fong, Jing Hong Menon, Shalisha Joy Jones, Gareth Iestyn Robert Karunaratne, Hettiyadura Apsara Surangani Mendis Non-typeable Haemophilus influenzae Osteomyelitis and Discitis of the Cervical Vertebrae in an Elderly Adult: A Case Report and Literature Review |
title | Non-typeable Haemophilus influenzae Osteomyelitis and Discitis of the Cervical Vertebrae in an Elderly Adult: A Case Report and Literature Review |
title_full | Non-typeable Haemophilus influenzae Osteomyelitis and Discitis of the Cervical Vertebrae in an Elderly Adult: A Case Report and Literature Review |
title_fullStr | Non-typeable Haemophilus influenzae Osteomyelitis and Discitis of the Cervical Vertebrae in an Elderly Adult: A Case Report and Literature Review |
title_full_unstemmed | Non-typeable Haemophilus influenzae Osteomyelitis and Discitis of the Cervical Vertebrae in an Elderly Adult: A Case Report and Literature Review |
title_short | Non-typeable Haemophilus influenzae Osteomyelitis and Discitis of the Cervical Vertebrae in an Elderly Adult: A Case Report and Literature Review |
title_sort | non-typeable haemophilus influenzae osteomyelitis and discitis of the cervical vertebrae in an elderly adult: a case report and literature review |
topic | Internal Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275657/ https://www.ncbi.nlm.nih.gov/pubmed/37332474 http://dx.doi.org/10.7759/cureus.39155 |
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