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Validation of the Non-Motor Symptoms Scale for Parkinson's Disease of Persian Version

OBJECTIVE: We aimed to assess the validity and reliability of the Persian version of the NonMotor Symptoms Scale (NMSS) in Iranian patients with PD. METHODS: This cross-sectional study was conducted in patients with PD. After the cross-cultural adaptation of the NMSS, the acceptability, reliability,...

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Autores principales: Eghlidos, Zahra, Abolhassanbeigi, Aida, Rahimian, Zahra, Khazraei, Samaneh, Ostovan, Vahid Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275686/
https://www.ncbi.nlm.nih.gov/pubmed/37333718
http://dx.doi.org/10.1155/2023/1972034
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author Eghlidos, Zahra
Abolhassanbeigi, Aida
Rahimian, Zahra
Khazraei, Samaneh
Ostovan, Vahid Reza
author_facet Eghlidos, Zahra
Abolhassanbeigi, Aida
Rahimian, Zahra
Khazraei, Samaneh
Ostovan, Vahid Reza
author_sort Eghlidos, Zahra
collection PubMed
description OBJECTIVE: We aimed to assess the validity and reliability of the Persian version of the NonMotor Symptoms Scale (NMSS) in Iranian patients with PD. METHODS: This cross-sectional study was conducted in patients with PD. After the cross-cultural adaptation of the NMSS, the acceptability, reliability, precision, and validity of the Persian NMSS were evaluated. For this purpose, in addition to NMSS, we used the following measures: Scales for Outcomes in Parkinson's Disease (SCOPA)-Autonomic (SCOPA-AUT), SCOPA-Sleep, Beck's Depression Inventory (BDI) questionnaire, Parkinson's Disease Questionnaire-8 questions (PDQ–8), SCOPA-Motor, SCOPA-Psychiatric Complications (SCOPA-PC), SCOPA-Cognition (SCOPA-COG), Mini-Mental State Examination (MMSE), Hoehn and Yahr Staging (H and Y), and Unified Parkinson Disease Rating Scale (UPDRS). RESULTS: 186 patients were enrolled (mean age 64.46 ± 9.9 years; disease duration 5.59 ± 3.99 years; 118 (63.4%) male; mean NMSS score 52.01 ± 38.54). Neither the floor effect (2.7%) nor the ceiling effect (0.5%) was seen in NMSS total score. Cronbach's alpha of total NMSS was 0.84. The test-retest reliability was 0.93 for the NMSS total and 0.81–0.96 for domains. The standard error of measurement (SEM) was lower than half of the standard deviation for NMSS total and all domains. NMSS total showed a high correlation with UPDRS I (r(s) = 0.84), UPDRS II (r(s) = 0.58), PDQ-8 (r(s) = 0.61), BDI (r(s) = 0.71), SCOPA-sleep (r(s) = 0.60), and SCOPA AUT (r(s) = 0.66). NMSS has an acceptable discriminative validity based on disease duration and severity of disease according to H and Y staging. CONCLUSION: The Persian NMSS is a valid and reliable measure for evaluating the burden of nonmotor symptoms in Iranian patients with PD.
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spelling pubmed-102756862023-06-17 Validation of the Non-Motor Symptoms Scale for Parkinson's Disease of Persian Version Eghlidos, Zahra Abolhassanbeigi, Aida Rahimian, Zahra Khazraei, Samaneh Ostovan, Vahid Reza Parkinsons Dis Research Article OBJECTIVE: We aimed to assess the validity and reliability of the Persian version of the NonMotor Symptoms Scale (NMSS) in Iranian patients with PD. METHODS: This cross-sectional study was conducted in patients with PD. After the cross-cultural adaptation of the NMSS, the acceptability, reliability, precision, and validity of the Persian NMSS were evaluated. For this purpose, in addition to NMSS, we used the following measures: Scales for Outcomes in Parkinson's Disease (SCOPA)-Autonomic (SCOPA-AUT), SCOPA-Sleep, Beck's Depression Inventory (BDI) questionnaire, Parkinson's Disease Questionnaire-8 questions (PDQ–8), SCOPA-Motor, SCOPA-Psychiatric Complications (SCOPA-PC), SCOPA-Cognition (SCOPA-COG), Mini-Mental State Examination (MMSE), Hoehn and Yahr Staging (H and Y), and Unified Parkinson Disease Rating Scale (UPDRS). RESULTS: 186 patients were enrolled (mean age 64.46 ± 9.9 years; disease duration 5.59 ± 3.99 years; 118 (63.4%) male; mean NMSS score 52.01 ± 38.54). Neither the floor effect (2.7%) nor the ceiling effect (0.5%) was seen in NMSS total score. Cronbach's alpha of total NMSS was 0.84. The test-retest reliability was 0.93 for the NMSS total and 0.81–0.96 for domains. The standard error of measurement (SEM) was lower than half of the standard deviation for NMSS total and all domains. NMSS total showed a high correlation with UPDRS I (r(s) = 0.84), UPDRS II (r(s) = 0.58), PDQ-8 (r(s) = 0.61), BDI (r(s) = 0.71), SCOPA-sleep (r(s) = 0.60), and SCOPA AUT (r(s) = 0.66). NMSS has an acceptable discriminative validity based on disease duration and severity of disease according to H and Y staging. CONCLUSION: The Persian NMSS is a valid and reliable measure for evaluating the burden of nonmotor symptoms in Iranian patients with PD. Hindawi 2023-06-09 /pmc/articles/PMC10275686/ /pubmed/37333718 http://dx.doi.org/10.1155/2023/1972034 Text en Copyright © 2023 Zahra Eghlidos et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Eghlidos, Zahra
Abolhassanbeigi, Aida
Rahimian, Zahra
Khazraei, Samaneh
Ostovan, Vahid Reza
Validation of the Non-Motor Symptoms Scale for Parkinson's Disease of Persian Version
title Validation of the Non-Motor Symptoms Scale for Parkinson's Disease of Persian Version
title_full Validation of the Non-Motor Symptoms Scale for Parkinson's Disease of Persian Version
title_fullStr Validation of the Non-Motor Symptoms Scale for Parkinson's Disease of Persian Version
title_full_unstemmed Validation of the Non-Motor Symptoms Scale for Parkinson's Disease of Persian Version
title_short Validation of the Non-Motor Symptoms Scale for Parkinson's Disease of Persian Version
title_sort validation of the non-motor symptoms scale for parkinson's disease of persian version
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275686/
https://www.ncbi.nlm.nih.gov/pubmed/37333718
http://dx.doi.org/10.1155/2023/1972034
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