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Dose finding study for on-demand HIV pre-exposure prophylaxis for insertive sex in sub-Saharan Africa: results from the CHAPS open label randomised controlled trial

BACKGROUND: The efficacy of on-demand HIV pre-exposure prophylaxis (PrEP) for men in sub-Saharan Africa has not been evaluated, and the on-demand PrEP dosing requirement for insertive sex remains unknown. METHODS: HIV-negative males 13–24 years, requesting voluntary medical male circumcision (VMMC),...

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Detalles Bibliográficos
Autores principales: Herrera, Carolina, Serwanga, Jennifer, Else, Laura, Limakatso, Lebina, Opoka, Daniel, Ssemata, Andrew S., Pillay, Azure-Dee, Namubiru, Patricia, Seiphetlo, Thabiso B., Odoch, Geoffrey, Mugaba, Susan, Seatlholo, Portia, Alieu, Amara, Penchala, Sujan Dilly, Muhumuza, Richard, Alinde, Berenice, Petkov, Stefan, O'Hagan, Kyle, Callebaut, Christian, Seeley, Janet, Weiss, Helen, Khoo, Saye, Chiodi, Francesca, Gray, Clive M., Kaleebu, Pontiano, Webb, Emily L., Martinson, Neil, Fox, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275696/
https://www.ncbi.nlm.nih.gov/pubmed/37327677
http://dx.doi.org/10.1016/j.ebiom.2023.104648