Integrative systems biology characterizes immune-mediated neurodevelopmental changes in murine Zika virus microcephaly

Characterizing perturbation of molecular pathways in congenital Zika virus (ZIKV) infection is critical for improved therapeutic approaches. Leveraging integrative systems biology, proteomics, and RNA-seq, we analyzed embryonic brain tissues from an immunocompetent, wild-type congenital ZIKV infecti...

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Detalles Bibliográficos
Autores principales: Fujimura, Kimino, Guise, Amanda J., Nakayama, Tojo, Schlaffner, Christoph N., Meziani, Anais, Kumar, Mukesh, Cheng, Long, Vaughan, Dylan J., Kodani, Andrew, Van Haren, Simon, Parker, Kenneth, Levy, Ofer, Durbin, Ann F., Bosch, Irene, Gehrke, Lee, Steen, Hanno, Mochida, Ganeshwaran H., Steen, Judith A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275723/
https://www.ncbi.nlm.nih.gov/pubmed/37332674
http://dx.doi.org/10.1016/j.isci.2023.106909

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