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Mass spectrometric simultaneous quantification of tau species in plasma shows differential associations with amyloid and tau pathologies

Blood phosphorylated tau (p-tau) biomarkers, at differing sites, demonstrate high accuracy to detect Alzheimerʼs disease (AD). However, knowledge on the optimal marker for disease identification across the AD continuum and the link to pathology is limited. This is partly due to heterogeneity in anal...

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Detalles Bibliográficos
Autores principales: Montoliu-Gaya, Laia, Benedet, Andréa L., Tissot, Cécile, Vrillon, Agathe, Ashton, Nicholas J., Brum, Wagner S., Lantero-Rodriguez, Juan, Stevenson, Jenna, Nilsson, Johanna, Sauer, Mathias, Rahmouni, Nesrine, Brinkmalm, Gunnar, Lussier, Firoza Z., Pascoal, Tharick A., Skoog, Ingmar, Kern, Silke, Zetterberg, Henrik, Paquet, Claire, Gobom, Johan, Rosa-Neto, Pedro, Blennow, Kaj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275761/
https://www.ncbi.nlm.nih.gov/pubmed/37198279
http://dx.doi.org/10.1038/s43587-023-00405-1

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