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Mass spectrometric simultaneous quantification of tau species in plasma shows differential associations with amyloid and tau pathologies
Blood phosphorylated tau (p-tau) biomarkers, at differing sites, demonstrate high accuracy to detect Alzheimerʼs disease (AD). However, knowledge on the optimal marker for disease identification across the AD continuum and the link to pathology is limited. This is partly due to heterogeneity in anal...
Autores principales: | Montoliu-Gaya, Laia, Benedet, Andréa L., Tissot, Cécile, Vrillon, Agathe, Ashton, Nicholas J., Brum, Wagner S., Lantero-Rodriguez, Juan, Stevenson, Jenna, Nilsson, Johanna, Sauer, Mathias, Rahmouni, Nesrine, Brinkmalm, Gunnar, Lussier, Firoza Z., Pascoal, Tharick A., Skoog, Ingmar, Kern, Silke, Zetterberg, Henrik, Paquet, Claire, Gobom, Johan, Rosa-Neto, Pedro, Blennow, Kaj |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275761/ https://www.ncbi.nlm.nih.gov/pubmed/37198279 http://dx.doi.org/10.1038/s43587-023-00405-1 |
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