Best Practices in Microbial Experimental Evolution: Using Reporters and Long-Read Sequencing to Identify Copy Number Variation in Experimental Evolution

Copy number variants (CNVs), comprising gene amplifications and deletions, are a pervasive class of heritable variation. CNVs play a key role in rapid adaptation in both natural, and experimental, evolution. However, despite the advent of new DNA sequencing technologies, detection and quantification...

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Detalles Bibliográficos
Autores principales: Spealman, Pieter, De, Titir, Chuong, Julie N., Gresham, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275804/
https://www.ncbi.nlm.nih.gov/pubmed/37012421
http://dx.doi.org/10.1007/s00239-023-10102-7

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