Dyrk2 gene transfer suppresses hepatocarcinogenesis by promoting the degradation of Myc and Hras

BACKGROUND & AIMS: Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide, and has a poor prognosis. However, the molecular mechanisms underlying hepatocarcinogenesis and progression remain unknown. In vitro gain- and loss-of-function analyses in cell lines and xenografts rev...

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Detalles Bibliográficos
Autores principales: Kamioka, Hiroshi, Yogosawa, Satomi, Oikawa, Tsunekazu, Aizawa, Daisuke, Ueda, Kaoru, Saeki, Chisato, Haruki, Koichiro, Shimoda, Masayuki, Ikegami, Toru, Nishikawa, Yuji, Saruta, Masayuki, Yoshida, Kiyotsugu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275997/
https://www.ncbi.nlm.nih.gov/pubmed/37333975
http://dx.doi.org/10.1016/j.jhepr.2023.100759

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10275997/
https://www.ncbi.nlm.nih.gov/pubmed/37333975
http://dx.doi.org/10.1016/j.jhepr.2023.100759

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