PEGylated Recombinant Adenosine Deaminase Maintains Detoxification and Lymphocyte Counts in Patients with ADA-SCID

PURPOSE: Metabolic detoxification with enzyme replacement therapy (ERT) promotes immune recovery in patients with adenosine deaminase (ADA)–deficient severe combined immunodeficiency (ADA-SCID). Elapegademase is a PEGylated recombinant bovine ADA ERT developed to replace the now-discontinued bovine-...

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Detalles Bibliográficos
Autores principales: Dorsey, Morna J., Rubinstein, Arye, Lehman, Heather, Fausnight, Tracy, Wiley, Joseph M., Haddad, Elie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276086/
https://www.ncbi.nlm.nih.gov/pubmed/36840835
http://dx.doi.org/10.1007/s10875-022-01426-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276086/
https://www.ncbi.nlm.nih.gov/pubmed/36840835
http://dx.doi.org/10.1007/s10875-022-01426-y

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