Cargando…

Mono- and di-acylated imidazolidine-2-thione derivatives: synthesis, cytotoxicity evaluation and computational studies

Imidazolidine-2-thione substructure represents a pharmaceutically attractive scaffold, being included in different antimicrobial, anticancer and pesticide agents. To further evaluate the pharmaceutical potential of this chemical moiety, imidazolidine-2-thione was reacted with atypical Vilsmeier addu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Scarsi, Anna, Ponassi, Marco, Brullo, Chiara, Rosano, Camillo, Spallarossa, Andrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276106/ https://www.ncbi.nlm.nih.gov/pubmed/35867289 http://dx.doi.org/10.1007/s11030-022-10487-5

Ejemplares similares

Regioselective Synthesis, Structural Characterization, and Antiproliferative Activity of Novel Tetra-Substituted Phenylaminopyrazole Derivatives
por: Lusardi, Matteo, et al.
Publicado: (2022)

1,3-Dibenzylimidazolidine-2-thione
por: Mietlarek-Kropidłowska, Anna, et al.
Publicado: (2012)

Bicyclic Basic Merbarone Analogues as Antiproliferative Agents
por: Spallarossa, Andrea, et al.
Publicado: (2021)

1-Methyl-3-phenylimidazolidine-2-thione
por: Nor, Nabihah Al Muna Mohd, et al.
Publicado: (2014)

Pentacarbonyl(imidazolidine-2-thione-κS)tungsten(0)
por: Merniz, Salah, et al.
Publicado: (2010)

The effect of S-alkylation on organocatalytic enamine activation through imidazolidine-4-thiones
por: Hensinger, Magenta J., et al.
Publicado: (2023)

Crystal structure of bis[(acetato-κO)(imidazolidine-2-thione-κS)bis(triphenylphosphane-κP)silver(I)] di-μ-imidazolidine-2-thione-κ(4) S:S-bis[(imidazolidine-2-thione-κS)bis(triphenylphosphane-κP)silver(I)] diacetate acetonitrile disolvate tetrahydrate
por: Nimthong-Roldán, Arunpatcha, et al.
Publicado: (2016)

1,3-Bis(1-phenylethyl)imidazolidine-2-thione
por: Umar, M. Naveed, et al.
Publicado: (2012)

1-[5-(Dimethylamino)-1-naphthylsulfonyl]imidazolidine-2-thione
por: Zhang, Yong, et al.
Publicado: (2010)

1,3-Bis(1-cyclohexylethyl)imidazolidine-2-thione
por: Umar, M. Naveed, et al.
Publicado: (2012)

trans-4,5-Dihydroxy-1,3-diphenylimidazolidine-2-thione
por: Zhang, Zhenfeng, et al.
Publicado: (2009)

Synthesis, Cytotoxicity, and Antileishmanial Activity of N,N'-Disubstituted Ethylenediamine and Imidazolidine Derivatives
por: de Carvalho, Gustavo S. G., et al.
Publicado: (2010)

trans-4,5-Dihydroxy-1,3-bis(4-methoxyphenyl)imidazolidine-2-thione
por: Zhang, Zhenfeng, et al.
Publicado: (2009)

Structural Diversity of Copper(II) Complexes with N-(2-Pyridyl)Imidazolidin-2-Ones(Thiones) and Their in Vitro Antitumor Activity
por: Balewski, Łukasz, et al.
Publicado: (2014)

A Methanol Extract of Scabiosa atropurpurea Enhances Doxorubicin Cytotoxicity against Resistant Colorectal Cancer Cells In Vitro
por: Ben Toumia, Imene, et al.
Publicado: (2020)

Synthesis of New Imidazolidin-2,4-dione and 2-Thioxo-imidazolidin-4-ones via C-Phenylglycine Derivatives
por: de Sousa Luis, José Alixandre, et al.
Publicado: (2009)

Dispirooxindoles Based on 2-Selenoxo-Imidazolidin-4-Ones: Synthesis, Cytotoxicity and ROS Generation Ability
por: Novotortsev, Vladimir K., et al.
Publicado: (2021)

Amino-Pyrazoles in Medicinal Chemistry: A Review
por: Lusardi, Matteo, et al.
Publicado: (2023)

Halogen, chalcogen, and hydrogen bonding in organoiodine cocrystals of heterocyclic thiones: imidazolidine-2-thione, 2-mercaptobenzimidazole, 2-mercapto-5-methylbenzimidazole, 2-mercaptobenzoxazole, and 2-mercaptobenzothiazole
por: Watts, Spencer, et al.
Publicado: (2022)

3-Amino-5,5-diphenylimidazolidine-2,4-dione
por: Mague, Joel T., et al.
Publicado: (2014)

3-Isobutyl-5,5-diphenylimidazolidine-2,4-dione
por: Guerrab, Walid, et al.
Publicado: (2022)

Synthesis and biological evaluation of novel imidazolidine derivatives as candidates to schistosomicidal agents
por: Matos-Rocha, Thiago José, et al.
Publicado: (2017)

Synthesis and Structure of Mono-, Di-, and Trinuclear Fluorotriarylbismuthonium Cations
por: Kuziola, Jennifer, et al.
Publicado: (2022)

The Development of BTK Inhibitors: A Five-Year Update
por: Tasso, Bruno, et al.
Publicado: (2021)

Targeting USP-7 by a Novel Fluorinated 5-Pyrazolyl-Urea Derivative
por: Morretta, Elva, et al.
Publicado: (2023)

Similar Membrane Affinity of Mono- and Di-S-acylated Ras Membrane Anchors: A New Twist in the Role of Protein Lipidation
por: Gorfe, Alemayehu A., et al.
Publicado: (2008)

Copper-catalyzed reaction of aziridine for the synthesis of substituted imidazolidine and imidazolidinone
por: Hashimoto, Kota, et al.
Publicado: (2023)

Synthesis and crystal structure of 3-phenyl-1,4,2-dithiazole-5-thione
por: Schriver, Melbourne J., et al.
Publicado: (2022)

Microbiological Evaluation of 4-substituted-imidazolidine Derivatives
por: Khan, M. S. Y., et al.
Publicado: (2012)

Structural diversity in copper(I) iodide complexes with 6-thioxopiperidin-2-one, piperidine-2,6-dithione and isoindoline-1,3-dithione ligands
por: Wheaton, Amelia M., et al.
Publicado: (2020)

Synthesis, Structure and Cytotoxic Activity of Mono- and Dialkoxy Derivatives of 5,8-Quinolinedione
por: Kadela, Monika, et al.
Publicado: (2016)

Btk Inhibitors: A Medicinal Chemistry and Drug Delivery Perspective
por: Brullo, Chiara, et al.
Publicado: (2021)

Nanotechnology of Tyrosine Kinase Inhibitors in Cancer Therapy: A Perspective
por: Russo, Eleonora, et al.
Publicado: (2021)

The Development of FAK Inhibitors: A Five-Year Update
por: Spallarossa, Andrea, et al.
Publicado: (2022)

Nanotechnology for Pediatric Retinoblastoma Therapy
por: Russo, Eleonora, et al.
Publicado: (2022)

4,5-Diferrocenyl-1,2-dithiole-3-thione
por: Sánchez-García, Jessica J., et al.
Publicado: (2022)

The Effects of Acyl Chain Length on Antioxidant Efficacy of Mono- and Multi-Acylated Resveratrol: A Comparative Assessment
por: Peng, Han, et al.
Publicado: (2022)

3-(2-Bromoethyl)-5,5-diphenylimidazolidine-2,4-dione
por: Guerrab, Walid, et al.
Publicado: (2023)

Synthesis Biological Evaluation of Quinazoline-4-thiones
por: Kubicová, Lenka, et al.
Publicado: (2003)

New Imidazolidineiminothione, Imidazolidin-2-one and Imidazoquinoxaline  Derivatives: Synthesis and Evaluation of Antibacterial and Antifungal Activities
por: Ammar, Yousry A., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_4sfs6t4vnaqiamgkssp3gereeb