Cargando…

Vulvar basal cell carcinoma: A case report and literature review

INTRODUCTION AND IMPORTANCE: Basal cell carcinoma (BCC), is the most prevalent skin cancer with favorable prognosis, and lymphatic or hematogenous metastases are quite rare. Here we report an uncommon case of vulvar BCC. CASE PRESENTATION: A 68-year-old woman with 5-year history of an asymptomatic l...

Descripción completa

Detalles Bibliográficos
Autores principales: Aminimoghadam, Soheila, Marzban, Zahra, Ghaemi, Marjan, Azizi, Sepideh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276133/
https://www.ncbi.nlm.nih.gov/pubmed/37311326
http://dx.doi.org/10.1016/j.ijscr.2023.108382
_version_ 1785060012367806464
author Aminimoghadam, Soheila
Marzban, Zahra
Ghaemi, Marjan
Azizi, Sepideh
author_facet Aminimoghadam, Soheila
Marzban, Zahra
Ghaemi, Marjan
Azizi, Sepideh
author_sort Aminimoghadam, Soheila
collection PubMed
description INTRODUCTION AND IMPORTANCE: Basal cell carcinoma (BCC), is the most prevalent skin cancer with favorable prognosis, and lymphatic or hematogenous metastases are quite rare. Here we report an uncommon case of vulvar BCC. CASE PRESENTATION: A 68-year-old woman with 5-year history of an asymptomatic lump on the right side of the vulva. The patient complained of progressive itching, pain, and color changes to brown for 3 months before visiting the clinic. Excisional biopsy revealed the lesion to be a BCC. After thorough negative metastasis work up the patient underwent a bilateral inguinofemoral lymphadenectomy and a wide local excision with a one-centimeter margin and final histology report confirmed the diagnosis of BCC. (HPV DNA and viral markers were negative, the bimanual exam was normal, both colposcopy and vaginoscopy were normal. There was no acetowhite lesion). CLINICAL DISCUSSION: To avoid delayed diagnosis, any persistent lesion even asymptomatic, in the vulvar region, especially when pigmented, irritating, or expanding in size, should be biopsied and investigated histologically, regardless of the patient's age. CONCLUSION: Any persistent lesion in the vulvar region, especially when pigmented, irritating, or expanding in size, should be biopsied and investigated histologically, regardless of the patient's age.
format Online
Article
Text
id pubmed-10276133
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-102761332023-06-18 Vulvar basal cell carcinoma: A case report and literature review Aminimoghadam, Soheila Marzban, Zahra Ghaemi, Marjan Azizi, Sepideh Int J Surg Case Rep Case Report INTRODUCTION AND IMPORTANCE: Basal cell carcinoma (BCC), is the most prevalent skin cancer with favorable prognosis, and lymphatic or hematogenous metastases are quite rare. Here we report an uncommon case of vulvar BCC. CASE PRESENTATION: A 68-year-old woman with 5-year history of an asymptomatic lump on the right side of the vulva. The patient complained of progressive itching, pain, and color changes to brown for 3 months before visiting the clinic. Excisional biopsy revealed the lesion to be a BCC. After thorough negative metastasis work up the patient underwent a bilateral inguinofemoral lymphadenectomy and a wide local excision with a one-centimeter margin and final histology report confirmed the diagnosis of BCC. (HPV DNA and viral markers were negative, the bimanual exam was normal, both colposcopy and vaginoscopy were normal. There was no acetowhite lesion). CLINICAL DISCUSSION: To avoid delayed diagnosis, any persistent lesion even asymptomatic, in the vulvar region, especially when pigmented, irritating, or expanding in size, should be biopsied and investigated histologically, regardless of the patient's age. CONCLUSION: Any persistent lesion in the vulvar region, especially when pigmented, irritating, or expanding in size, should be biopsied and investigated histologically, regardless of the patient's age. Elsevier 2023-06-02 /pmc/articles/PMC10276133/ /pubmed/37311326 http://dx.doi.org/10.1016/j.ijscr.2023.108382 Text en © 2023 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Aminimoghadam, Soheila
Marzban, Zahra
Ghaemi, Marjan
Azizi, Sepideh
Vulvar basal cell carcinoma: A case report and literature review
title Vulvar basal cell carcinoma: A case report and literature review
title_full Vulvar basal cell carcinoma: A case report and literature review
title_fullStr Vulvar basal cell carcinoma: A case report and literature review
title_full_unstemmed Vulvar basal cell carcinoma: A case report and literature review
title_short Vulvar basal cell carcinoma: A case report and literature review
title_sort vulvar basal cell carcinoma: a case report and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276133/
https://www.ncbi.nlm.nih.gov/pubmed/37311326
http://dx.doi.org/10.1016/j.ijscr.2023.108382
work_keys_str_mv AT aminimoghadamsoheila vulvarbasalcellcarcinomaacasereportandliteraturereview
AT marzbanzahra vulvarbasalcellcarcinomaacasereportandliteraturereview
AT ghaemimarjan vulvarbasalcellcarcinomaacasereportandliteraturereview
AT azizisepideh vulvarbasalcellcarcinomaacasereportandliteraturereview