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Vulvar basal cell carcinoma: A case report and literature review
INTRODUCTION AND IMPORTANCE: Basal cell carcinoma (BCC), is the most prevalent skin cancer with favorable prognosis, and lymphatic or hematogenous metastases are quite rare. Here we report an uncommon case of vulvar BCC. CASE PRESENTATION: A 68-year-old woman with 5-year history of an asymptomatic l...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276133/ https://www.ncbi.nlm.nih.gov/pubmed/37311326 http://dx.doi.org/10.1016/j.ijscr.2023.108382 |
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author | Aminimoghadam, Soheila Marzban, Zahra Ghaemi, Marjan Azizi, Sepideh |
author_facet | Aminimoghadam, Soheila Marzban, Zahra Ghaemi, Marjan Azizi, Sepideh |
author_sort | Aminimoghadam, Soheila |
collection | PubMed |
description | INTRODUCTION AND IMPORTANCE: Basal cell carcinoma (BCC), is the most prevalent skin cancer with favorable prognosis, and lymphatic or hematogenous metastases are quite rare. Here we report an uncommon case of vulvar BCC. CASE PRESENTATION: A 68-year-old woman with 5-year history of an asymptomatic lump on the right side of the vulva. The patient complained of progressive itching, pain, and color changes to brown for 3 months before visiting the clinic. Excisional biopsy revealed the lesion to be a BCC. After thorough negative metastasis work up the patient underwent a bilateral inguinofemoral lymphadenectomy and a wide local excision with a one-centimeter margin and final histology report confirmed the diagnosis of BCC. (HPV DNA and viral markers were negative, the bimanual exam was normal, both colposcopy and vaginoscopy were normal. There was no acetowhite lesion). CLINICAL DISCUSSION: To avoid delayed diagnosis, any persistent lesion even asymptomatic, in the vulvar region, especially when pigmented, irritating, or expanding in size, should be biopsied and investigated histologically, regardless of the patient's age. CONCLUSION: Any persistent lesion in the vulvar region, especially when pigmented, irritating, or expanding in size, should be biopsied and investigated histologically, regardless of the patient's age. |
format | Online Article Text |
id | pubmed-10276133 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-102761332023-06-18 Vulvar basal cell carcinoma: A case report and literature review Aminimoghadam, Soheila Marzban, Zahra Ghaemi, Marjan Azizi, Sepideh Int J Surg Case Rep Case Report INTRODUCTION AND IMPORTANCE: Basal cell carcinoma (BCC), is the most prevalent skin cancer with favorable prognosis, and lymphatic or hematogenous metastases are quite rare. Here we report an uncommon case of vulvar BCC. CASE PRESENTATION: A 68-year-old woman with 5-year history of an asymptomatic lump on the right side of the vulva. The patient complained of progressive itching, pain, and color changes to brown for 3 months before visiting the clinic. Excisional biopsy revealed the lesion to be a BCC. After thorough negative metastasis work up the patient underwent a bilateral inguinofemoral lymphadenectomy and a wide local excision with a one-centimeter margin and final histology report confirmed the diagnosis of BCC. (HPV DNA and viral markers were negative, the bimanual exam was normal, both colposcopy and vaginoscopy were normal. There was no acetowhite lesion). CLINICAL DISCUSSION: To avoid delayed diagnosis, any persistent lesion even asymptomatic, in the vulvar region, especially when pigmented, irritating, or expanding in size, should be biopsied and investigated histologically, regardless of the patient's age. CONCLUSION: Any persistent lesion in the vulvar region, especially when pigmented, irritating, or expanding in size, should be biopsied and investigated histologically, regardless of the patient's age. Elsevier 2023-06-02 /pmc/articles/PMC10276133/ /pubmed/37311326 http://dx.doi.org/10.1016/j.ijscr.2023.108382 Text en © 2023 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Aminimoghadam, Soheila Marzban, Zahra Ghaemi, Marjan Azizi, Sepideh Vulvar basal cell carcinoma: A case report and literature review |
title | Vulvar basal cell carcinoma: A case report and literature review |
title_full | Vulvar basal cell carcinoma: A case report and literature review |
title_fullStr | Vulvar basal cell carcinoma: A case report and literature review |
title_full_unstemmed | Vulvar basal cell carcinoma: A case report and literature review |
title_short | Vulvar basal cell carcinoma: A case report and literature review |
title_sort | vulvar basal cell carcinoma: a case report and literature review |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10276133/ https://www.ncbi.nlm.nih.gov/pubmed/37311326 http://dx.doi.org/10.1016/j.ijscr.2023.108382 |
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